Literature DB >> 19041416

Therapeutic potential of interleukin-15: a myokine involved in muscle wasting and adiposity.

Josep M Argilés1, Francisco J López-Soriano, Sílvia Busquets.   

Abstract

Since the discovery of IL-15 and its role in T-cell proliferation in 1994, different studies on the effects of the cytokine on metabolic effects have been performed. These studies have mainly been involved with the metabolic pathways involved in lipid and protein metabolism. The present review summarises the metabolic effects of IL-15 at different target tissues and the possibilities and potential for therapeutic interventions based on the cytokine's roles in obesity and wasting.

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Year:  2008        PMID： 19041416     DOI： 10.1016/j.drudis.2008.10.010

Source DB:  PubMed          Journal:  Drug Discov Today        ISSN： 1359-6446            Impact factor:   7.851


  18 in total

1.  Myokine IL-15 regulates the crosstalk of co-cultured porcine skeletal muscle satellite cells and preadipocytes.

Authors:  Yinghui Li; Fengna Li; Binbin Lin; Xiangfeng Kong; Yulong Tang; Yulong Yin
Journal:  Mol Biol Rep       Date:  2014-08-07       Impact factor: 2.316

2.  Modulation of endothelial cell proliferation and capillary network formation by the ox-LDL component: 1-palmitoyl-2-archidonoyl-sn-glycero-3-phosphocholine (ox-PAPC).

Authors:  B Kiec-Wilk; A Polus; U Razny; U Cialowicz; A Dembinska-Kiec
Journal:  Genes Nutr       Date:  2011-01-15       Impact factor: 5.523

3.  Prostaglandin E2: from clinical applications to its potential role in bone- muscle crosstalk and myogenic differentiation.

Authors:  Chenglin Mo; Sandra Romero-Suarez; Lynda Bonewald; Mark Johnson; Marco Brotto
Journal:  Recent Pat Biotechnol       Date:  2012-12

4.  Attenuation of Allergen-, IL-13-, and TGF-α-induced Lung Fibrosis after the Treatment of rIL-15 in Mice.

Authors:  Sathisha Upparahalli Venkateshaiah; Rituraj Niranjan; Murli Manohar; Alok K Verma; Hemanth K Kandikattu; Joseph A Lasky; Anil Mishra
Journal:  Am J Respir Cell Mol Biol       Date:  2019-07       Impact factor: 6.914

5.  Targeted loss of GHR signaling in mouse skeletal muscle protects against high-fat diet-induced metabolic deterioration.

Authors:  Archana Vijayakumar; YingJie Wu; Hui Sun; Xiaosong Li; Zuha Jeddy; Chengyu Liu; Gary J Schwartz; Shoshana Yakar; Derek LeRoith
Journal:  Diabetes       Date:  2012-01       Impact factor: 9.461

Review 6.  Cancer-Mediated Muscle Cachexia: Etiology and Clinical Management.

Authors:  Thomas Siff; Parash Parajuli; Mohammed S Razzaque; Azeddine Atfi
Journal:  Trends Endocrinol Metab       Date:  2021-04-19       Impact factor: 10.586

7.  Activation of TRPV1 channel by dietary capsaicin improves visceral fat remodeling through connexin43-mediated Ca2+ influx.

Authors:  Jian Chen; Li Li; Yingsha Li; Xia Liang; Qianqian Sun; Hao Yu; Jian Zhong; Yinxing Ni; Jing Chen; Zhigang Zhao; Peng Gao; Bin Wang; Daoyan Liu; Zhiming Zhu; Zhencheng Yan
Journal:  Cardiovasc Diabetol       Date:  2015-02-13       Impact factor: 9.951

8.  Molecular characterization and quantification using state of the art solid-state adiabatic TOBSY NMR in burn trauma.

Authors:  Valeria Righi; Ovidiu Andronesi; Dionyssios Mintzopoulos; A Aria Tzika
Journal:  Int J Mol Med       Date:  2009-12       Impact factor: 4.101

9.  Effects of Eccentric and Concentric Emphasized Resistance Exercise on IL-15 Serum Levels and Its Relation to Inflammatory Markers in Athletes and Non-Athletes.

Authors:  Behzad Bazgir; Mohsen Salesi; Maryam Koushki; Zahra Amirghofran
Journal:  Asian J Sports Med       Date:  2015-09-28

Review 10.  Nonmuscle Tissues Contribution to Cancer Cachexia.

Authors:  Josep M Argilés; Britta Stemmler; Francisco J López-Soriano; Silvia Busquets
Journal:  Mediators Inflamm       Date:  2015-10-07       Impact factor: 4.711
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