OBJECTIVE: To assess whether body mass index (BMI), waist circumference (WC) and waist to hip ratio (WRH) are associated to the steroid receptor status in breast carcinomas. METHODS: Four hundred and seventy three women with breast malignancies stage I-III were included. Weight, height, the waist and hip circumferences (WC), body mass index (BMI), and the waist to hip ratio (WHR) were determined. The expression of estrogen (ER) and progesterone (PR) receptors was determined with immunohistochemistry. RESULTS: Most women had central obesity (WC>or=88 and WHR>or=0.85 in 64.3 and 73.4%, respectively). The majority (78.1%) of the women had tumors that expressed at least one of the HR. BMI, WC and WHP were not related to the HR status in neither the pre- or postmenopausal women. Multivariate analysis confirmed these findings. CONCLUSIONS: BMI, WC or WHR may not be good predictors of HR status in breast malignancies in either pre- or postmenopausal women.
OBJECTIVE: To assess whether body mass index (BMI), waist circumference (WC) and waist to hip ratio (WRH) are associated to the steroid receptor status in breast carcinomas. METHODS: Four hundred and seventy three women with breast malignancies stage I-III were included. Weight, height, the waist and hip circumferences (WC), body mass index (BMI), and the waist to hip ratio (WHR) were determined. The expression of estrogen (ER) and progesterone (PR) receptors was determined with immunohistochemistry. RESULTS: Most women had central obesity (WC>or=88 and WHR>or=0.85 in 64.3 and 73.4%, respectively). The majority (78.1%) of the women had tumors that expressed at least one of the HR. BMI, WC and WHP were not related to the HR status in neither the pre- or postmenopausal women. Multivariate analysis confirmed these findings. CONCLUSIONS: BMI, WC or WHR may not be good predictors of HR status in breast malignancies in either pre- or postmenopausal women.
Authors: Kami K White; Song-Yi Park; Laurence N Kolonel; Brian E Henderson; Lynne R Wilkens Journal: Int J Cancer Date: 2012-01-27 Impact factor: 7.396
Authors: Daniel María Lubián López; Carmen Aisha Butrón Hinojo; María Castillo Lara; Manuel Sánchez-Prieto; Rafael Sánchez-Borrego; Nicolas Mendoza Ladrón de Guevara; Ernesto González Mesa Journal: Sci Rep Date: 2021-01-21 Impact factor: 4.379