Literature DB >> 1903875

Proteinases in Trichomonas vaginalis and Tritrichomonas mobilensis are not exclusively of cysteine type.

P Bózner1, P Demes.   

Abstract

High molecular weight proteinases of Trichomonas vaginalis (with apparent Mr values 142 and greater than 220 kDa) and Tritrichomonas mobilensis (Mr 67, 86, 104 and 120 kDa), optimally active at pH8, were analysed in gelatin-containing polyacrylamide gels. All of these proteinases were resistant to serine-, aspartic- as well as cysteine proteinase inhibitors. Both proteolytic bands in T. vaginalis and two proteinases in T. mobilensis (67 and 104 kDa) were inhibited by EDTA and EGTA suggesting that they belong to the metallo-proteinase class. The 67 kDa proteinase of T. mobilensis was inhibited also by o-phenanthroline. The other two bands of T. mobilensis (86, 120 kDa) were not classified to any proteinase group since they appeared to be resistant to the chelating agents tested in this study.

Entities:  

Mesh：

Substances：

Year:  1991        PMID： 1903875     DOI： 10.1017/s0031182000060418

Source DB:  PubMed          Journal:  Parasitology        ISSN： 0031-1820            Impact factor:   3.234


  9 in total

Review 1.  Mucinases and sialidases: their role in the pathogenesis of sexually transmitted infections in the female genital tract.

Authors:  R Wiggins; S J Hicks; P W Soothill; M R Millar; A P Corfield
Journal:  Sex Transm Infect       Date:  2001-12       Impact factor: 3.519

2.  20S Proteasome as a Drug Target in Trichomonas vaginalis.

Authors:  Anthony J O'Donoghue; Betsaida Bibo-Verdugo; Yukiko Miyamoto; Steven C Wang; Justin Z Yang; Douglas E Zuill; Shoun Matsuka; Zhenze Jiang; Jehad Almaliti; Conor R Caffrey; William H Gerwick; Lars Eckmann
Journal:  Antimicrob Agents Chemother       Date:  2019-10-22       Impact factor: 5.191

3.  CP30, a cysteine proteinase involved in Trichomonas vaginalis cytoadherence.

Authors:  M R Mendoza-López; C Becerril-Garcia; L V Fattel-Facenda; L Avila-Gonzalez; M E Ruíz-Tachiquín; J Ortega-Lopez; R Arroyo
Journal:  Infect Immun       Date:  2000-09       Impact factor: 3.441

4.  Analysis of human immunoglobulin-degrading cysteine proteinases of Trichomonas vaginalis.

Authors:  D Provenzano; J F Alderete
Journal:  Infect Immun       Date:  1995-09       Impact factor: 3.441

5.  Contact-independent cytotoxicity of Trichomonas vaginalis.

Authors:  F F Pindak; M Mora de Pindak; W A Gardner
Journal:  Genitourin Med       Date:  1993-02

6.  Serum antibodies to Trichomonas vaginalis in invasive cervical cancer patients.

Authors:  E H Yap; T H Ho; Y C Chan; T W Thong; G C Ng; L C Ho; M Singh
Journal:  Genitourin Med       Date:  1995-12

7.  TvMP50 is an immunogenic metalloproteinase during male trichomoniasis.

Authors:  Laura Itzel Quintas-Granados; José Luis Villalpando; Laura Isabel Vázquez-Carrillo; Rossana Arroyo; Guillermo Mendoza-Hernández; María Elizbeth Alvarez-Sánchez
Journal:  Mol Cell Proteomics       Date:  2013-04-11       Impact factor: 5.911

8.  Host-parasite interaction: parasite-derived and -induced proteases that degrade human extracellular matrix.

Authors:  Carolina Piña-Vázquez; Magda Reyes-López; Guillermo Ortíz-Estrada; Mireya de la Garza; Jesús Serrano-Luna
Journal:  J Parasitol Res       Date:  2012-06-26

9.  Putrescine-dependent re-localization of TvCP39, a cysteine proteinase involved in Trichomonas vaginalis cytotoxicity.

Authors:  Bertha Isabel Carvajal-Gamez; Laura Itzel Quintas-Granados; Rossana Arroyo; Laura Isabel Vázquez-Carrillo; Lucero De los Angeles Ramón-Luing; Eduardo Carrillo-Tapia; María Elizbeth Alvarez-Sánchez
Journal:  PLoS One       Date:  2014-09-24       Impact factor: 3.240
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.