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Literature DB >> 19038272

Benefits and risks of transforming data from dynamic positron emission tomography, with an application to hepatic encephalopathy.

Ludvik Bass¹, Susanne Keiding, Ole L Munk.

Abstract

Transforming data sets to bring out expected model features can be valuable within limits and misleading outside them. Here we establish such limits for the widely used Gjedde-Patlak representation of dynamic PET data, with an application to hepatic encephalopathy.

Entities: Chemical Disease Gene Species

Mesh：

Substances：
Radiopharmaceuticals

Year: 2008 PMID： 19038272 PMCID： PMC3032217 DOI： 10.1016/j.jtbi.2008.10.022

Source DB: PubMed Journal: J Theor Biol ISSN： 0022-5193 Impact factor: 2.691

12 in total

1. Liver kinetics of glucose analogs measured in pigs by PET: importance of dual-input blood sampling.

Authors: O L Munk; L Bass; K Roelsgaard; D Bender; S B Hansen; S Keiding
Journal: J Nucl Med Date: 2001-05 Impact factor: 10.057

2. Capillaries within compartments: microvascular interpretation of dynamic positron emission tomography data.

Authors: Ole Lajord Munk; Susanne Keiding; Ludvik Bass
Journal: J Theor Biol Date: 2003-11-07 Impact factor: 2.691

3. Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography.

Authors: Susanne Keiding; Michael Sørensen; Dirk Bender; Ole Lajord Munk; Peter Ott; Hendrik Vilstrup
Journal: Hepatology Date: 2006-01 Impact factor: 17.425

4. Factors which affect cerebral uptake and retention of 13NH3.

Authors: M E Phelps; E J Hoffman; C Raybaud
Journal: Stroke Date: 1977 Nov-Dec Impact factor: 7.914

5. The penetration of inulin, sucrose, mannitol and tritiated water from the interstitial space in muscle into the vascular system.

Authors: C Crone; D Garlick
Journal: J Physiol Date: 1970-09 Impact factor: 5.182

6. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data.

Authors: C S Patlak; R G Blasberg; J D Fenstermacher
Journal: J Cereb Blood Flow Metab Date: 1983-03 Impact factor: 6.200

7. The significance of the NH3-NH+(4) equilibrium on the passage of 13N-ammonia from blood to brain. A new regional residue detection model.

Authors: M E Raichle; K B Larson
Journal: Circ Res Date: 1981-06 Impact factor: 17.367

Benefits and risks of transforming data from dynamic positron emission tomography, with an application to hepatic encephalopathy.

1. Liver kinetics of glucose analogs measured in pigs by PET: importance of dual-input blood sampling.

2. Capillaries within compartments: microvascular interpretation of dynamic positron emission tomography data.

3. Brain metabolism of 13N-ammonia during acute hepatic encephalopathy in cirrhosis measured by positron emission tomography.

4. Factors which affect cerebral uptake and retention of 13NH3.

5. The penetration of inulin, sucrose, mannitol and tritiated water from the interstitial space in muscle into the vascular system.

6. Graphical evaluation of blood-to-brain transfer constants from multiple-time uptake data.

7. The significance of the NH3-NH+(4) equilibrium on the passage of 13N-ammonia from blood to brain. A new regional residue detection model.

8. Metabolites of (18)F-FDG and 3-O-(11)C-methylglucose in pig liver.

9. Calculation of cerebral glucose phosphorylation from brain uptake of glucose analogs in vivo: a re-examination.

Review 10. Blood-brain barrier permeability to ammonia in liver failure: a critical reappraisal.

1. Human (13)N-ammonia PET studies: the importance of measuring (13)N-ammonia metabolites in blood.