Literature DB >> 19037887

Canine dilated cardiomyopathy: a retrospective study of signalment, presentation and clinical findings in 369 cases.

M W S Martin1, M J Stafford Johnson, B Celona.   

Abstract

OBJECTIVE: To review the clinical and diagnostic findings and survival of dilated cardiomyopathy from a large population of dogs in England.
METHODS: A retrospective study of the case records of dogs with dilated cardiomyopathy collected between January 1993 and May 2006.
RESULTS: There were 369 dogs with dilated cardiomyopathy of which all were pure-bred dogs except for four. The most commonly affected breeds were dobermanns and boxers. Over 95 per cent of dogs weighed more than 15 kg and 73 per cent were male. The median duration of signs before referral was three weeks with 65 per cent presenting in stage 3 heart failure. The most common signs were breathlessness (67 per cent) and coughing (64 per cent). The majority of dogs (89 per cent) had an arrhythmia at presentation and 74 per cent of dogs had radiographic signs of pulmonary oedema or pleural effusion. The median survival time was 19 weeks. CLINICAL SIGNIFICANCE: Dilated cardiomyopathy occurs primarily in medium to large breed pure-bred dogs, and males are more frequently affected than females. The duration of clinical signs before referral is often short and the survival times are poor. Greater awareness of affected breeds, clinical signs and diagnostic findings may help in early recognition of this disease which often has a short clinical phase.

Entities:  

Mesh:

Year:  2008        PMID: 19037887     DOI: 10.1111/j.1748-5827.2008.00659.x

Source DB:  PubMed          Journal:  J Small Anim Pract        ISSN: 0022-4510            Impact factor:   1.522


  16 in total

1.  Effect of type of diet on blood and plasma taurine concentrations, cardiac biomarkers, and echocardiograms in 4 dog breeds.

Authors:  Darcy Adin; Lisa Freeman; Rebecca Stepien; John E Rush; Sonja Tjostheim; Heidi Kellihan; Michael Aherne; Michelle Vereb; Robert Goldberg
Journal:  J Vet Intern Med       Date:  2021-02-27       Impact factor: 3.333

2.  Multiple Genetic Associations with Irish Wolfhound Dilated Cardiomyopathy.

Authors:  Siobhan Simpson; Mark D Dunning; Serena Brownlie; Janika Patel; Megan Godden; Malcolm Cobb; Nigel P Mongan; Catrin S Rutland
Journal:  Biomed Res Int       Date:  2016-12-13       Impact factor: 3.411

3.  Welfare-Adjusted Life Years (WALY): A novel metric of animal welfare that combines the impacts of impaired welfare and abbreviated lifespan.

Authors:  Kendy Tzu-Yun Teng; Brecht Devleesschauwer; Charline Maertens De Noordhout; Peter Bennett; Paul D McGreevy; Po-Yu Chiu; Jenny-Ann L M L Toribio; Navneet K Dhand
Journal:  PLoS One       Date:  2018-09-12       Impact factor: 3.240

4.  Intracoronary Gene Delivery of the Cytoprotective Factor Vascular Endothelial Growth Factor-B167 in Canine Patients with Dilated Cardiomyopathy: A Short-Term Feasibility Study.

Authors:  Paola Paradies; Lucia Carlucci; Felix Woitek; Francesco Staffieri; Luca Lacitignola; Luigi Ceci; Daniela Romano; Mariateresa Sasanelli; Lorena Zentilin; Mauro Giacca; Stefano Salvadori; Antonio Crovace; Fabio A Recchia
Journal:  Vet Sci       Date:  2019-03-06

5.  Retrospective study of dilated cardiomyopathy in dogs.

Authors:  Kimberly J Freid; Lisa M Freeman; John E Rush; Suzanne M Cunningham; Megan S Davis; Emily T Karlin; Vicky K Yang
Journal:  J Vet Intern Med       Date:  2020-12-21       Impact factor: 3.175

6.  Origins of the domestic dog and the rich potential for gene mapping.

Authors:  Jeremy R Shearman; Alan N Wilton
Journal:  Genet Res Int       Date:  2011-01-17

Review 7.  Genetics of Human and Canine Dilated Cardiomyopathy.

Authors:  Siobhan Simpson; Jennifer Edwards; Thomas F N Ferguson-Mignan; Malcolm Cobb; Nigel P Mongan; Catrin S Rutland
Journal:  Int J Genomics       Date:  2015-07-22       Impact factor: 2.326

8.  Longevity and mortality in Kennel Club registered dog breeds in the UK in 2014.

Authors:  T W Lewis; B M Wiles; A M Llewellyn-Zaidi; K M Evans; D G O'Neill
Journal:  Canine Genet Epidemiol       Date:  2018-10-17

9.  Development of plasma and whole blood taurine reference ranges and identification of dietary features associated with taurine deficiency and dilated cardiomyopathy in golden retrievers: A prospective, observational study.

Authors:  Eric S Ontiveros; Bradley D Whelchel; Joshua Yu; Joanna L Kaplan; Ashley N Sharpe; Samantha L Fousse; Amanda E Crofton; Andrea J Fascetti; Joshua A Stern
Journal:  PLoS One       Date:  2020-05-15       Impact factor: 3.240

Review 10.  Review of canine dilated cardiomyopathy in the wake of diet-associated concerns.

Authors:  Sydney R McCauley; Stephanie D Clark; Bradley W Quest; Renee M Streeter; Eva M Oxford
Journal:  J Anim Sci       Date:  2020-06-01       Impact factor: 3.159

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