| Literature DB >> 19037751 |
Babak Arjmand1, Seyed Hamidreza Aghayan, Parisa Goodarzi, Mohammad Farzanehkhah, Seyed Mohamadjavad Mortazavi, Mohamad Hossein Niknam, Ali Jafarian, Farzin Arjmand, Soheyla Jebelly far.
Abstract
Iranian Tissue Bank prepares a wide range of human tissue homografts such as; heart valve, bone, skin, amniotic membrane and other tissues for different clinical applications. The purpose of this study was to determine the seroprevalence of HTLV in tissue donors. About 1,548 tissue donors were studied during a 5-years period by ELISA assays. HTLV(1,2)-antibodies were tested for all of donors with other tests upon American Association of Tissue Banks (AATB) standards. About 25 (1.61%) out of 1,548 tissue donors were HTLV positive that 17 donors were male and 8 were female (female/male ratio was approximately 47%). Regarding to the prevalence of HTLV among tissue donors and importance of cell and tissue safety and quality assurance, we recommend that all blood, cell and tissue banks should be involved both routine serological methods and other complementary tests such as polymerase chain reaction (PCR) for diagnosis of HTLV.Entities:
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Year: 2008 PMID： 19037751 DOI： 10.1007/s10561-008-9117-9
Source DB: PubMed Journal: Cell Tissue Bank ISSN： 1389-9333 Impact factor: 1.522