Literature DB >> 19037519

Gram-negative resistance in Singapore: a historical perspective.

Tse Hsien Koh1.   

Abstract

In the past 3 decades, classical extended-spectrum beta-lactamases (ESBLs) have probably been the main contributors to gram-negative antimicrobial resistance in Singapore. These appear to be being replaced by the newer CTX-M ESBLs. Metallo-beta-lactamases are found in Pseudomonas aeruginosa but do not seem to have spread widely in Acinetobacter spp. and Enterobacteriaceae. Carbapenem-hydrolysing oxacillinases are prevalent in multidrug-resistant Acinetobacter spp. More insidious developments include the emergence of plasmid AmpC beta-lactamases and multifactorial quinolone resistance in Enterobacteriaceae.

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Year:  2008        PMID: 19037519

Source DB:  PubMed          Journal:  Ann Acad Med Singapore        ISSN: 0304-4602            Impact factor:   2.473


  8 in total

1.  Molecular characterization of newly emerged blaKPC-2-producing Klebsiella pneumoniae in Singapore.

Authors:  Michelle N D Balm; Grace Ngan; Roland Jureen; Raymond T P Lin; Jeanette Teo
Journal:  J Clin Microbiol       Date:  2011-11-23       Impact factor: 5.948

Review 2.  Ten-year narrative review on antimicrobial resistance in Singapore.

Authors:  Alvin Qijia Chua; Andrea Lay-Hoon Kwa; Thean Yen Tan; Helena Legido-Quigley; Li Yang Hsu
Journal:  Singapore Med J       Date:  2019-08       Impact factor: 1.858

Review 3.  Acinetobacter baumannii-associated skin and soft tissue infections: recognizing a broadening spectrum of disease.

Authors:  Dubert M Guerrero; Federico Perez; Nicholas G Conger; Joseph S Solomkin; Mark D Adams; Philip N Rather; Robert A Bonomo
Journal:  Surg Infect (Larchmt)       Date:  2010-02       Impact factor: 2.150

4.  Surveillance and correlation of antibiotic prescription and resistance of Gram-negative bacteria in Singaporean hospitals.

Authors:  Li-Yang Hsu; Thean-Yen Tan; Vincent H Tam; Andrea Kwa; Dale Andrew Fisher; Tse-Hsien Koh
Journal:  Antimicrob Agents Chemother       Date:  2010-01-11       Impact factor: 5.191

5.  Comparable outcomes for β-lactam/β-lactamase inhibitor combinations and carbapenems in definitive treatment of bloodstream infections caused by cefotaxime-resistant Escherichia coli or Klebsiella pneumoniae.

Authors:  Patrick N A Harris; Mo Yin; Roland Jureen; Jonathan Chew; Jaminah Ali; Stuart Paynter; David L Paterson; Paul A Tambyah
Journal:  Antimicrob Resist Infect Control       Date:  2015-05-01       Impact factor: 4.887

Review 6.  Klebsiella pneumoniae in Singapore: Hypervirulent Infections and the Carbapenemase Threat.

Authors:  Ka Lip Chew; Raymond T P Lin; Jeanette W P Teo
Journal:  Front Cell Infect Microbiol       Date:  2017-12-12       Impact factor: 5.293

7.  OXA-181-producing Klebsiella pneumoniae establishing in Singapore.

Authors:  Michelle N D Balm; Grace Ngan; Roland Jureen; Raymond T P Lin; Jeanette W P Teo
Journal:  BMC Infect Dis       Date:  2013-02-01       Impact factor: 3.090

8.  Epidemiology and molecular characterization of multidrug-resistant Gram-negative bacteria in Southeast Asia.

Authors:  Nuntra Suwantarat; Karen C Carroll
Journal:  Antimicrob Resist Infect Control       Date:  2016-05-04       Impact factor: 4.887

  8 in total

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