Literature DB >> 19036594

A new antiangiogenic C24 oxylipin from the soft coral Sinularia numerosa.

Takahiro Yamashita1, Yoichi Nakao, Shigeki Matsunaga, Tsutomu Oikawa, Yukimitsu Imahara, Nobuhiro Fusetani.   

Abstract

A new oxylipin, 15-hydroxy-tetracosa-6,9,12,16,18-pentaenoic acid (15-HTPE; 1) was isolated as an inhibitor of tube-formation from the soft coral Sinularia numerosa. Its structure was elucidated by means of spectral analysis and chemical degradation. 15-HTPE inhibited tube formation of EA.hy926 cells at the concentration of 20-40 microM.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19036594     DOI： 10.1016/j.bmc.2008.10.083

Source DB:  PubMed          Journal:  Bioorg Med Chem        ISSN： 0968-0896            Impact factor:   3.641


  4 in total

Review 1.  Marine unsaturated fatty acids: structures, bioactivities, biosynthesis and benefits.

Authors:  Yingfang Lu; Yinning Chen; Yulin Wu; Huili Hao; Wenjing Liang; Jun Liu; Riming Huang
Journal:  RSC Adv       Date:  2019-10-31       Impact factor: 4.036

Review 2.  Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2013-07-16       Impact factor: 5.118

3.  New sinularianin sesquiterpenes from soft coral Sinularia sp.

Authors:  Bin Yang; Shengrong Liao; Xiuping Lin; Junfeng Wang; Juan Liu; Xuefeng Zhou; Xianwen Yang; Yonghong Liu
Journal:  Mar Drugs       Date:  2013-12-02       Impact factor: 5.118

4.  Norcembranoidal diterpenes from the cultured-type octocoral Sinularia numerosa.

Authors:  Wu-Fu Chen; Chen-Ting Yin; Ching-Hsiao Cheng; Mei-Chin Lu; Lee-Shing Fang; Wei-Hsien Wang; Zhi-Hong Wen; Jih-Jung Chen; Yang-Chang Wu; Ping-Jyun Sung
Journal:  Int J Mol Sci       Date:  2015-02-03       Impact factor: 5.923
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.