Literature DB >> 19036336

Anion channels: regulation of ClC-3 by an orphan second messenger.

Alexi K Alekov1, Christoph Fahlke.   

Abstract

ClC-3 is a ubiquitously expressed chloride channel isoform whose biological function has been a matter of debate for many years. A recent study reporting its regulation by Ins(3,4,5,6)P(4) assigns novel transport functions and cellular roles to ClC-3 and identifies a regulatory pathway that affects epithelial transport and endosomal pH regulation.

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Year:  2008        PMID： 19036336     DOI： 10.1016/j.cub.2008.09.023

Source DB:  PubMed          Journal:  Curr Biol        ISSN： 0960-9822            Impact factor:   10.834


  6 in total

Review 1.  Clues and new evidences in arterial hypertension: unmasking the role of the chloride anion.

Authors:  Nicolás Martín Kouyoumdzian; Gabriel Kim; María Julieta Rudi; Natalia Lucía Rukavina Mikusic; Belisario Enrique Fernández; Marcelo Roberto Choi
Journal:  Pflugers Arch       Date:  2021-12-30       Impact factor: 3.657

2.  Functional regulation of ClC-3 in the migration of vascular smooth muscle cells.

Authors:  Sindura B Ganapathi; Shun-Guang Wei; Angelika Zaremba; Fred S Lamb; Stephen B Shears
Journal:  Hypertension       Date:  2012-11-12       Impact factor: 10.190

Review 3.  Chloride channels: often enigmatic, rarely predictable.

Authors:  Charity Duran; Christopher H Thompson; Qinghuan Xiao; H Criss Hartzell
Journal:  Annu Rev Physiol       Date:  2010       Impact factor: 19.318

4.  The Concise Guide to PHARMACOLOGY 2013/14: ion channels.

Authors:  Stephen P H Alexander; Helen E Benson; Elena Faccenda; Adam J Pawson; Joanna L Sharman; William A Catterall; Michael Spedding; John A Peters; Anthony J Harmar
Journal:  Br J Pharmacol       Date:  2013-12       Impact factor: 8.739

5.  Novel CLC3 transcript variants in blood eosinophils and increased CLC3 expression in nasal lavage and blood eosinophils of asthmatics.

Authors:  Rohit Gaurav; Againdra K Bewtra; Devendra K Agrawal
Journal:  Immun Inflamm Dis       Date:  2014-12-04

6.  Channel-like slippage modes in the human anion/proton exchanger ClC-4.

Authors:  Alexi K Alekov; Christoph Fahlke
Journal:  J Gen Physiol       Date:  2009-04-13       Impact factor: 4.086
  6 in total

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