Literature DB >> 19031477

Factors related to perceived quality of life in patients with Alzheimer's disease: the patient's perception compared with that of caregivers.

Josep Lluís Conde-Sala1, Josep Garre-Olmo, Oriol Turró-Garriga, Secundino López-Pousa, Joan Vilalta-Franch.   

Abstract

AIMS: To compare care recipient and caregiver perceptions of quality of life in patients (QoL-p) with Alzheimer's disease (AD). To identify associated factors, and the concordances-discrepancies.
METHOD: Cross-sectional analytic study of 236 patients and their carers using the Quality of Life in Alzheimer's Disease (QoL-AD) scale, socio-demographic data and clinical examination.
RESULTS: Patients scored the QoL-AD more favourably than did caregivers (34.4 vs 31.3, p < 0.001). Cognitive deterioration did not affect the perception of QoL-AD (rho = -0.05, p = 0.394). The neuropsychiatric symptoms was associated with a negative perception of the QOL-AD in both patients (rho = -0.22, p < 0.01) and caregivers (rho = -0.47, p < 0.001). Greater functional autonomy was associated with a better perception of the QOL-AD in patients (rho = 0.17, p < 0.01) and even more so in caregivers (rho = 0.56, p < 0.001). In carers, burden (rho = -0.56, p < 0.001) and mental health (rho = 0.31, p < 0.001) were inversely associated with the QoL-AD. QoL-AD scores of both patients and caregivers were higher for men, married subjects, those who lived with their spouse and those living in their own home. When the carer was a spouse both patients and caregivers scored the QoL-AD higher than when the carer was a son or daughter (35.5 vs 33.4 and 33.7; 32.9 vs 30.5 and 27.7, p < 0.001).
CONCLUSIONS: Patients have a better perception of QoL-p. Caregivers give a more negative evaluation of neuropsychiatric symptoms, but have a more positive view of functional autonomy. Carers who are spouses have a better perception of QoL-p than do carers who are sons or daughters. (c) 2008 John Wiley & Sons, Ltd.

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Year:  2009        PMID: 19031477     DOI: 10.1002/gps.2161

Source DB:  PubMed          Journal:  Int J Geriatr Psychiatry        ISSN: 0885-6230            Impact factor:   3.485


  40 in total

1.  Predictors of patient self-ratings of quality of life in Alzheimer disease: cross-sectional results from the Canadian Alzheimer's Disease Quality of Life Study.

Authors:  Gary Naglie; David B Hogan; Murray Krahn; B Lynn Beattie; Sandra E Black; Chris Macknight; Morris Freedman; Christopher Patterson; Michael Borrie; Howard Bergman; Anna Byszewski; David Streiner; Jane Irvine; Paul Ritvo; Janna Comrie; Matthew Kowgier; George Tomlinson
Journal:  Am J Geriatr Psychiatry       Date:  2011-10       Impact factor: 4.105

2.  Predictors of family caregiver ratings of patient quality of life in Alzheimer disease: cross-sectional results from the Canadian Alzheimer's Disease Quality of Life Study.

Authors:  Gary Naglie; David B Hogan; Murray Krahn; Sandra E Black; B Lynn Beattie; Christopher Patterson; Chris Macknight; Morris Freedman; Michael Borrie; Anna Byszewski; Howard Bergman; David Streiner; Jane Irvine; Paul Ritvo; Janna Comrie; Matthew Kowgier; George Tomlinson
Journal:  Am J Geriatr Psychiatry       Date:  2011-10       Impact factor: 4.105

3.  Incongruent perceptions of pain and physical function among families living with lung cancer.

Authors:  Lyndsey M Miller; Karen S Lyons; Jill A Bennett
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4.  Domains of quality of life in Alzheimer's disease vary according to caregiver kinship.

Authors:  Marcela M L Nogueira; Jose Pedro Simões Neto; Marcia C N Dourado
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5.  Participant-Informant Relationships Affect Quality of Life Ratings in Incipient and Clinical Alzheimer Disease.

Authors:  Amy Lin; Jenny Brook; Joshua D Grill; Edmond Teng
Journal:  Am J Geriatr Psychiatry       Date:  2016-10-13       Impact factor: 4.105

6.  Concordance of self- and proxy-rated worry and anxiety symptoms in older adults with dementia.

Authors:  Andrea Bradford; Gretchen A Brenes; Roberta A Robinson; Nancy Wilson; A Lynn Snow; Mark E Kunik; Jessica Calleo; Nancy J Petersen; Melinda A Stanley; Amber B Amspoker
Journal:  J Anxiety Disord       Date:  2012-11-23

7.  Acute Affective Reactivity and Quality of Life in Older Adults with Amnestic Mild Cognitive Impairment: A Functional MRI Study.

Authors:  Ping Ren; Kathi L Heffner; Alanna Jacobs; Feng Lin
Journal:  Am J Geriatr Psychiatry       Date:  2017-06-27       Impact factor: 4.105

8.  Early Cognitively Based Functional Limitations Predict Loss of Independence in Instrumental Activities of Daily Living in Older Adults.

Authors:  Karen M Lau; Mili Parikh; Danielle J Harvey; Chun-Jung Huang; Sarah Tomaszewski Farias
Journal:  J Int Neuropsychol Soc       Date:  2015-09-22       Impact factor: 2.892

9.  Effect of study partner on the conduct of Alzheimer disease clinical trials.

Authors:  Joshua D Grill; Rema Raman; Karin Ernstrom; Paul Aisen; Jason Karlawish
Journal:  Neurology       Date:  2012-12-19       Impact factor: 9.910

10.  Generic quality of life assessment in dementia patients: a prospective cohort study.

Authors:  Claudia Schiffczyk; Barbara Romero; Christina Jonas; Constanze Lahmeyer; Friedemann Müller; Matthias W Riepe
Journal:  BMC Neurol       Date:  2010-06-20       Impact factor: 2.474

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