Literature DB >> 19030458

A new generation of anticonvulsants for the treatment of epilepsy in children.

O Carter Snead1, Elizabeth J Donner.   

Abstract

Over the past 12 years, a number of new anticonvulsant drugs have been introduced for the treatment of childhood epilepsy. The present article reviews these new agents and provides the considerations one should use in selecting an antiepileptic drug for use in children. While in some cases the newer antiepileptic drugs have a more favourable pharmacokinetic and toxicity profile than the older drugs, there appears to be no objective evidence that any currently available antiepileptic drug is superior in terms of therapeutic efficacy.

Entities:  

Keywords:  Antiepileptic drug; Epilepsy; Epilepsy syndromes; Seizure; Status epilepticus

Year:  2007        PMID： 19030458      PMCID： PMC2532866          DOI： 10.1093/pch/12.9.741

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN： 1205-7088            Impact factor:   2.253


  30 in total

1.  A double-blind, randomized trial of topiramate as adjunctive therapy for partial-onset seizures in children. Topiramate YP Study Group.

Authors:  R D Elterman; T A Glauser; E Wyllie; R Reife; S C Wu; G Pledger
Journal:  Neurology       Date:  1999-04-22       Impact factor: 9.910

2.  [Cognitive consequences of Rolandic Epilepsy].

Authors:  A D Saint-Martin; C Seegmuller; R Carcangiu; C Kleitz; E Hirsch; C Marescaux; M N Metz-Lutz
Journal:  Epileptic Disord       Date:  2001       Impact factor: 1.819

3.  Dose-dependent safety and efficacy of zonisamide: a randomized, double-blind, placebo-controlled study in patients with refractory partial seizures.

Authors:  Martin J Brodie; Roderick Duncan; Herve Vespignani; Andras Solyom; Valeriy Bitenskyy; Cherry Lucas
Journal:  Epilepsia       Date:  2005-01       Impact factor: 5.864

4.  Levetiracetam-induced myoclonic status epilepticus in myoclonic-astatic epilepsy: a case report.

Authors:  Judith Kröll-Seger; Ian William Mothersill; Simon Novak; Ritva Anneli Sälke-Kellermann; Günter Krämer
Journal:  Epileptic Disord       Date:  2006-09       Impact factor: 1.819

5.  Lamotrigine for generalized seizures associated with the Lennox-Gastaut syndrome. Lamictal Lennox-Gastaut Study Group.

Authors:  J Motte; E Trevathan; J F Arvidsson; M N Barrera; E L Mullens; P Manasco
Journal:  N Engl J Med       Date:  1997-12-18       Impact factor: 91.245

6.  Topiramate pharmacokinetics in children and adults with epilepsy: a case-matched comparison based on therapeutic drug monitoring data.

Authors:  Dina Battino; Danilo Croci; Alessandro Rossini; Sara Messina; Daniela Mamoli; Emilio Perucca
Journal:  Clin Pharmacokinet       Date:  2005       Impact factor: 6.447

7.  Levetiracetam in patients with generalised epilepsy and myoclonic seizures: an open label study.

Authors:  Angelo Labate; Eleonora Colosimo; Antonio Gambardella; Ugo Leggio; Roberta Ambrosio; Aldo Quattrone
Journal:  Seizure       Date:  2006-01-18       Impact factor: 3.184

8.  Reduced visual function associated with infantile spasms in children on vigabatrin therapy.

Authors:  Dena S Hammoudi; Sophia S F Lee; Adena Madison; Giuseppe Mirabella; J Raymond Buncic; William J Logan; O Carter Snead; Carol A Westall
Journal:  Invest Ophthalmol Vis Sci       Date:  2005-02       Impact factor: 4.799

Review 9.  Practice parameter: medical treatment of infantile spasms: report of the American Academy of Neurology and the Child Neurology Society.

Authors:  M T Mackay; S K Weiss; T Adams-Webber; S Ashwal; D Stephens; K Ballaban-Gill; T Z Baram; M Duchowny; D Hirtz; J M Pellock; W D Shields; S Shinnar; E Wyllie; O C Snead
Journal:  Neurology       Date:  2004-05-25       Impact factor: 9.910

Review 10.  Hyponatremia associated with carbamazepine and oxcarbazepine therapy: a review.

Authors:  T Van Amelsvoort; R Bakshi; C B Devaux; S Schwabe
Journal:  Epilepsia       Date:  1994 Jan-Feb       Impact factor: 5.864
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  4 in total

1.  "Epileptic encephalopathy" of infancy and childhood: electro-clinical pictures and recent understandings.

Authors:  Pasquale Parisi; Alberto Spalice; Francesco Nicita; Laura Papetti; Fabiana Ursitti; Alberto Verrotti; Paola Iannetti; Maria Pia Villa
Journal:  Curr Neuropharmacol       Date:  2010-12       Impact factor: 7.363

2.  Healthcare Resource Utilization Pre- and Post-Initiation of Eslicarbazepine Acetate Among Pediatric Patients with Focal Seizure: Evidence from Routine Clinical Practice.

Authors:  Darshan Mehta; Matthew Davis; Andrew J Epstein; G Rhys Williams
Journal:  Clinicoecon Outcomes Res       Date:  2020-07-23

3.  Epileptic encephalopathies in adults and childhood.

Authors:  Zekiye Kural; Ali Fahir Ozer
Journal:  Epilepsy Res Treat       Date:  2012-09-27

Review 4.  Pain management strategies for neuropathic pain in Fabry disease--a systematic review.

Authors:  Y Schuller; G E Linthorst; C E M Hollak; I N Van Schaik; M Biegstraaten
Journal:  BMC Neurol       Date:  2016-02-24       Impact factor: 2.474
  4 in total

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