Literature DB >> 19030311

Seven fatal varicella infections in children were potentially avoidable: A report from IMPACT centres from 2000 to 2005.

David W Scheifele1, Barbara Law, Scott A Halperin, Theresa Tam.   

Abstract

A varicella vaccine for children has been readily available in Canada since 2000, but some parents and physicians doubt the need for it. The Immunization Monitoring Program, ACTive (IMPACT) network of pediatric hospitals tabulated 1900 varicella-related hospitalizations and seven varicella-related deaths from 2000 to 2005. The present report describes these fatal cases, demonstrating the unpredictable and avoidable nature of life-threatening varicella complications. The knowledge that healthy children can die of chickenpox could influence parents to accept the recommended vaccination. Deaths from varicella should cease to occur, given the safe alternative of, and free access to, vaccination in current provincial programs.

Entities:  

Keywords:  Chickenpox; Chickenpox vaccine; Immunizations; Preventive care; Varicella

Year:  2006        PMID： 19030311      PMCID： PMC2528628     

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN： 1205-7088            Impact factor:   2.253


  5 in total

1.  The Immunization Monitoring Program Active (IMPACT) prospective five year study of Canadian children hospitalized for chickenpox or an associated complication.

Authors:  B Law; N MacDonald; S Halperin; D Scheifele; P Déry; T Jadavji; M H Lebel; E Mills; R Morris; W Vaudry; R Gold; V Marchessault; P Duclos
Journal:  Pediatr Infect Dis J       Date:  2000-11       Impact factor: 2.129

2.  Decline in varicella-related hospitalizations and expenditures for children and adults after introduction of varicella vaccine in the United States.

Authors:  Matthew M Davis; Mitesh S Patel; Achamyeleh Gebremariam
Journal:  Pediatrics       Date:  2004-09       Impact factor: 7.124

3.  Disparities in varicella vaccine coverage in the absence of public funding.

Authors:  Reka Gustafson; Danuta M Skowronski
Journal:  Vaccine       Date:  2005-05-20       Impact factor: 3.641

4.  Incidence of herpes zoster, before and after varicella-vaccination-associated decreases in the incidence of varicella, 1992-2002.

Authors:  Aisha O Jumaan; Onchee Yu; Lisa A Jackson; Kari Bohlke; Karin Galil; Jane F Seward
Journal:  J Infect Dis       Date:  2005-05-12       Impact factor: 5.226

5.  Persistence of immunity to live attenuated varicella vaccine in healthy adults.

Authors:  Krow Ampofo; Lisa Saiman; Philip LaRussa; Sharon Steinberg; Paula Annunziato; Anne Gershon
Journal:  Clin Infect Dis       Date:  2002-02-04       Impact factor: 9.079
  5 in total

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