Literature DB >> 19030247

Antibiotic choices by paediatric residents and recently graduated paediatricians for typical infectious disease problems in children.

Katharine Smart1, Jean-Francois Lemay, James D Kellner.   

Abstract

OBJECTIVE: To evaluate antibiotic choices and recommendations for duration of therapy made by paediatric residents (PRs) and recently graduated paediatricians (RGPs) in several typical infectious disease conditions.
METHODS: In autumn 2002, a two-page questionnaire was sent to 276 core PRs in Canadian residency programs and to a random selection of 276 RGPs from across Canada. The questionnaire described 10 scenarios: otitis media, pharyngitis, sinusitis, bronchopneumonia, lobar pneumonia, meningitis, pyelonephritis, osteomyelitis, cellulitis, and fever and neutropenia. The participants were asked primarily about initial antibiotic selection and duration of treatment for each scenario.
RESULTS: There were 251 participants (overall response rate of 45%). The two most common antibiotic recommendations constituted 85% or more of the total for all scenarios except acute otitis media, sinusitis, cellulitis, and fever and neutropenia. There was a twofold or more difference in the range of recommended duration of treatment for all scenarios and a threefold or more difference for sinusitis, meningitis and osteomyelitis. PRs were more likely than RGPs to use broader spectrum cephalosporins for pneumococcal pneumonia (33% versus 15%, respectively; P=0.001) and to treat sinusitis for just five to 10 days (39% versus 22%, respectively; P=0.01). Also, 33% of all participants recommended amoxicillin/clavulanate or a cephalosporin rather than amoxicillin for sinusitis.
CONCLUSION: PRs and RGPs made similar and reasonable recommendations, largely in line with published guidelines, for most of the infectious disease scenarios presented. For some conditions, a significant minority of respondents unnecessarily recommended broad-spectrum antibiotics. The most variable responses were for duration of treatment, reflecting the lack of certainty in the published evidence base for many conditions.

Entities:  

Keywords:  Antibiotic prescribing; Clinical practice guidelines; Paediatric residents; Survey

Year:  2006        PMID: 19030247      PMCID: PMC2528600     

Source DB:  PubMed          Journal:  Paediatr Child Health        ISSN: 1205-7088            Impact factor:   2.253


  31 in total

1.  Antibiotic utilization at the university hospital after introducing an antibiotic policy.

Authors:  V Vlahovic-Palcevski; M Morovic; G Palcevski
Journal:  Eur J Clin Pharmacol       Date:  2000-04       Impact factor: 2.953

2.  2002 guidelines for the use of antimicrobial agents in neutropenic patients with cancer.

Authors:  Walter T Hughes; Donald Armstrong; Gerald P Bodey; Eric J Bow; Arthur E Brown; Thierry Calandra; Ronald Feld; Philip A Pizzo; Kenneth V I Rolston; Jerry L Shenep; Lowell S Young
Journal:  Clin Infect Dis       Date:  2002-02-13       Impact factor: 9.079

3.  Practice guidelines for the diagnosis and management of group A streptococcal pharyngitis. Infectious Diseases Society of America.

Authors:  Alan L Bisno; Michael A Gerber; Jack M Gwaltney; Edward L Kaplan; Richard H Schwartz
Journal:  Clin Infect Dis       Date:  2002-07-15       Impact factor: 9.079

Review 4.  Mode of questionnaire administration can have serious effects on data quality.

Authors:  Ann Bowling
Journal:  J Public Health (Oxf)       Date:  2005-05-03       Impact factor: 2.341

5.  Otitis media-related antibiotic prescribing patterns, outcomes, and expenditures in a pediatric medicaid population.

Authors:  S Berman; P J Byrns; J Bondy; P J Smith; D Lezotte
Journal:  Pediatrics       Date:  1997-10       Impact factor: 7.124

6.  Bacteriologic response to oral cephalosporins: are established susceptibility breakpoints appropriate in the case of acute otitis media?

Authors:  R Dagan; O Abramson; E Leibovitz; D Greenberg; R Lang; S Goshen; P Yagupsky; A Leiberman; D M Fliss
Journal:  J Infect Dis       Date:  1997-11       Impact factor: 5.226

7.  Polypharmacy and poisons in pediatrics--the epidemic of overprescribing and ways to control it.

Authors:  G B Stickler
Journal:  Adv Pediatr       Date:  1980

8.  Antibiotic prescribing by pediatricians for respiratory tract infection in children.

Authors:  S R Arnold; U D Allen; M Al-Zahrani; D H Tan; E E Wang
Journal:  Clin Infect Dis       Date:  1999-08       Impact factor: 9.079

9.  Reduction in antibiotic use among US children, 1996-2000.

Authors:  Jonathan A Finkelstein; Christopher Stille; James Nordin; Robert Davis; Marsha A Raebel; Douglas Roblin; Alan S Go; David Smith; Christine C Johnson; Kenneth Kleinman; K Arnold Chan; Richard Platt
Journal:  Pediatrics       Date:  2003-09       Impact factor: 7.124

Review 10.  Acute otitis media: management and surveillance in an era of pneumococcal resistance--a report from the Drug-resistant Streptococcus pneumoniae Therapeutic Working Group.

Authors:  S F Dowell; J C Butler; G S Giebink; M R Jacobs; D Jernigan; D M Musher; A Rakowsky; B Schwartz
Journal:  Pediatr Infect Dis J       Date:  1999-01       Impact factor: 2.129

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