Literature DB >> 19028743

Outcome of orbital decompression for disfiguring proptosis in patients with Graves' orbitopathy using various surgical procedures.

M P Mourits, H Bijl, M A Altea, L Baldeschi, K Boboridis, N Currò, A J Dickinson, A Eckstein, M Freidel, C Guastella, G J Kahaly, R Kalmann, G E Krassas, C M Lane, J Lareida, C Marcocci, M Marino, M Nardi, Ch Mohr, C Neoh, A Pinchera, J Orgiazzi, S Pitz, P Saeed, M Salvi, S Sellari-Franceschini, M Stahl, G von Arx, W M Wiersinga.   

Abstract

AIM: To compare the outcome of various surgical approaches of orbital decompression in patients with Graves' orbitopathy (GO) receiving surgery for disfiguring proptosis.
METHOD: Data forms and questionnaires from consecutive, euthyroid patients with inactive GO who had undergone orbital decompression for disfiguring proptosis in 11 European centres were analysed.
RESULTS: Eighteen different (combinations of) approaches were used, the swinging eyelid approach being the most popular followed by the coronal and transconjunctival approaches. The average proptosis reduction for all decompressions was 5.0 (SD 2.1) mm. After three-wall decompression the proptosis reduction was significantly greater than after two-wall decompression. Additional fat removal resulted in greater proptosis reduction. Complications were rare, the most frequent being worsening of motility, occurring more frequently after coronal decompression. The average change in quality of life (QOL) in the appearance arm of the GO-QOL questionnaire was 20.5 (SD 24.8) points.
CONCLUSIONS: In Europe, a wide range of surgical approaches is used to reduce disfiguring proptosis in patients with GO. The extent of proptosis reduction depends on the number of walls removed and whether or not fat is removed. Serious complications are infrequent. Worsening of ocular motility is still a major complication, but was rare in this series after the swinging eyelid approach.

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Year:  2008        PMID: 19028743     DOI: 10.1136/bjo.2008.149302

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  30 in total

1.  Ocular changes and approaches of ophthalmopathy in basedow - graves- parry- flajani disease.

Authors:  George Saraci; Anamaria Treta
Journal:  Maedica (Buchar)       Date:  2011-04

2.  [Surgical therapy in Graves' orbitopathy].

Authors:  J Kaminsky; G J Ridder; A Eckstein; M Metzger; F Beisse
Journal:  Ophthalmologe       Date:  2011-05       Impact factor: 1.059

3.  Thyroid-stimulating immunoglobulins indicate the onset of dysthyroid optic neuropathy.

Authors:  K A Ponto; T Diana; H Binder; N Matheis; S Pitz; N Pfeiffer; G J Kahaly
Journal:  J Endocrinol Invest       Date:  2015-03-04       Impact factor: 4.256

Review 4.  Orbital Decompression for Thyroid Eye Disease.

Authors:  Tara L Braun; Mohin A Bhadkamkar; Kevin T Jubbal; Adam C Weber; Douglas P Marx
Journal:  Semin Plast Surg       Date:  2017-02       Impact factor: 2.314

5.  Pharmacotherapy: does selenium supplementation improve Graves ophthalmopathy?

Authors:  Terry J Smith; Raymond S Douglas
Journal:  Nat Rev Endocrinol       Date:  2011-08-02       Impact factor: 43.330

6.  Surgical Outcomes of Balanced Deep Lateral and Medial Orbital Wall Decompression in Korean Population: Clinical and Computed Tomography-based Analysis.

Authors:  Sang Uk Choi; Kyoung Woo Kim; Jeong Kyu Lee
Journal:  Korean J Ophthalmol       Date:  2016-03-25

7.  Endoscopic orbital fat decompression for the management of proptosis in Grave's orbitopathy using a laryngeal skimmer blade.

Authors:  David S Curragh; Dinesh Selva
Journal:  Eye (Lond)       Date:  2019-07-08       Impact factor: 3.775

8.  Proposal for Standardization of Primary and Secondary Outcomes in Patients with Active, Moderate-to-Severe Graves' Orbitopathy.

Authors:  Luigi Bartalena; Wilmar M Wiersinga
Journal:  Eur Thyroid J       Date:  2020-09-21

9.  Feasibility of tomotherapy for Graves' ophthalmopathy: Dosimetry comparison with conventional radiotherapy.

Authors:  Nam P Nguyen; Shane P Krafft; Paul Vos; Vincent Vinh-Hung; Misty Ceizyk; Siyoung Jang; Anand Desai; Dave Abraham; Lars Ewell; Christopher Watchman; Russ Hamilton; Beng-Hoey Jo; Ulf Karlsson; Lexie Smith-Raymond
Journal:  Strahlenther Onkol       Date:  2011-06-28       Impact factor: 3.621

10.  Thyroid-Related Orbital Decompression Surgery: A Multivariate Analysis of Risk Factors and Outcomes.

Authors:  Chris Y Wu; Leslie M Niziol; David C Musch; Alon Kahana
Journal:  Ophthalmic Plast Reconstr Surg       Date:  2017 May/Jun       Impact factor: 1.746

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