| Literature DB >> 19027298 |
P Prabhakar Reddy1, R Ranga Rao, K Rekha, K Suresh Babu, J Shashidhar, G Shashikiran, V Vijaya Lakshmi, J Madhusudana Rao.
Abstract
Phytochemical investigation of CHCl(3) extract of the rhizomes of Hedychium spicatum led to the isolation of two new labdane-type diterpenes, compounds 1 and 2 along with five known compounds (3-7). Their structures were established on the basis of NMR (1D and 2D) and mass spectroscopic analysis. In addition, all the isolates were tested for their cytotoxicity against the Colo-205 (Colo-cancer), A-431 (skin cancer), MCF-7 (breast cancer), A-549 (lung cancer) and Chinese hamster ovary cells (CHO). Two new compounds 1 and 2 were shown good cytotoxic activity.Entities:
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Year: 2008 PMID： 19027298 DOI： 10.1016/j.bmcl.2008.10.121
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823