Acute ischemic stroke management: administration of thrombolytics, neuroprotectants, and general principles of medical management.

The pathophysiology of acute ischemic stroke involves occlusion of a cerebral artery; therefore, cerebral reperfusion is the primary goal of acute treatment. This article discusses established and emerging therapies for acute ischemic stroke. In addition to thrombolysis, acute treatment with antiplatelet agents and other medications and neuroprotection are reviewed. The general medical management of acute ischemic stroke patients is also reviewed.