Literature DB >> 19026193

Isolated full thickness chondral injuries. Prevalance and outcome of treatment. A retrospective study of 5233 knee arthroscopies.

W Widuchowski1, P Lukasik, G Kwiatkowski, R Faltus, K Szyluk, J Widuchowski, B Koczy.   

Abstract

PURPOSE OF THE STUDY The aim of this study was to provide data on the prevalence and epidemiology of isolated deep chondral lesions of the knee, diagnosed in arthroscopy. The study was also aimed to analyse subjective treatment results of localized deep isolated cartilage lesions and to determine how the different factors might affect the final outcome. MATERIAL AND METHODS From 1997 to 2002, 5233 knee arthroscopies were performed. The first part of the study is an epidemiological and statistical analysis of the isolated articular cartilage lesions in which we used the questionnaire based on the International Knee Documentation Committee (IKDC) Questionnaire. The second part is the analysis of subjective treatment evaluation. For this purpose the IKDC criteria were used. Following aspects were taken into account: lesion location and size, time after surgery, patients' age, performed surgical cartilage procedure. The follow-up period ranged from 1 to 7 years. The statistical analysis was performed with the use of the Pearson correlation coefficient and t-test. Significance was set at p<0.05. RESULTS In the analyzed material cartilage lesion was diagnosed in 2931 patients (57.3%). Isolated localized chondral Outerbridge grade 3 and 4 lesions were documented in 5.2% of all patients with diagnosed cartilage lesion. The patellar articular surface (37.5%) and the medial femoral condyle (32.2%) were the most frequent localizations of these lesions. There was no correlation between the results and the period of time after arthroscopy. The best results were obtained in cases of loose body removal, debridement, mosaicplasty and also in cases where the lesion was left untreated. DISCUSSION The management of full-thickness cartilage injury remains one of the most difficult problems in the orthopedic surgery, particularly isolated and symptomatic. In 7 years of follow-up we found good and satisfactory results when debridement and loose body removal was performed and when the lesions was left untreated. Significantly the worst results in subjective evaluation we observed in marrow-stimulating procedures. This study confirms that the appropriate qualification for treatment plays the most important role in successive management of cartilage injuries. CONCLUSIONS Treatment of isolated deep chondral lesions of the knee remains a questionable issue. Little invasive arthroscopic methods as well as using no surgical treatment in grade 3 and 4 isolated cartilage lesions may be effective and improve symptoms and knee function at mid-term follow-up.Our data support also the contention that the natural history of cartilage lesions still remains unpredictable and not well understood.

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Year:  2008        PMID: 19026193

Source DB:  PubMed          Journal:  Acta Chir Orthop Traumatol Cech        ISSN: 0001-5415            Impact factor:   0.531


  25 in total

Review 1.  Staging and comorbidities.

Authors:  Christian Lattermann; Matthew R Luckett
Journal:  J Knee Surg       Date:  2011-12       Impact factor: 2.757

2.  The Scaffold-Articular Cartilage Interface: A Combined In Vitro and In Silico Analysis Under Controlled Loading Conditions.

Authors:  Tony Chen; Moira M McCarthy; Hongqiang Guo; Russell Warren; Suzanne A Maher
Journal:  J Biomech Eng       Date:  2018-09-01       Impact factor: 2.097

3.  Effects of immobilization and remobilization on the ankle joint in Wistar rats.

Authors:  R I Kunz; J G Coradini; L I Silva; G R F Bertolini; R M C Brancalhão; L F C Ribeiro
Journal:  Braz J Med Biol Res       Date:  2014-08-15       Impact factor: 2.590

Review 4.  Decellularized tissue and cell-derived extracellular matrices as scaffolds for orthopaedic tissue engineering.

Authors:  Christina W Cheng; Loran D Solorio; Eben Alsberg
Journal:  Biotechnol Adv       Date:  2014-01-10       Impact factor: 14.227

Review 5.  [Repair of local cartilage defects in the patellofemoral joint].

Authors:  S Anders; P Lechler; J Grifka; J Schaumburger
Journal:  Orthopade       Date:  2011-10       Impact factor: 1.087

6.  Effectiveness and limitations of autologous osteochondral grafting for the treatment of articular cartilage defects in the knee.

Authors:  Shinji Imade; Nobuyuki Kumahashi; Suguru Kuwata; Jyunji Iwasa; Yuji Uchio
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2011-07-12       Impact factor: 4.342

7.  New and Emerging Techniques in Cartilage Repair: MACI.

Authors:  Brad S Dunkin; Christian Lattermann
Journal:  Oper Tech Sports Med       Date:  2013-06-01       Impact factor: 0.280

8.  The cost utility of autologous chondrocytes implantation using ChondroCelect® in symptomatic knee cartilage lesions in Belgium.

Authors:  Laetitia Gerlier; Mark Lamotte; Micheline Wille; Peter C Kreuz; Johan Vanlauwe; Dominique Dubois; François M Meurgey
Journal:  Pharmacoeconomics       Date:  2010       Impact factor: 4.981

Review 9.  Early osteoarthritis of the patellofemoral joint.

Authors:  Elizabeth A Arendt; Massimo Berruto; Giuseppe Filardo; Mario Ronga; Stefano Zaffagnini; Jack Farr; Paolo Ferrua; Alberto Grassi; Vincenzo Condello
Journal:  Knee Surg Sports Traumatol Arthrosc       Date:  2016-04-27       Impact factor: 4.342

10.  Autologous osteochondral transplantation for the treatment of knee lesions: results and limitations at two years' follow-up.

Authors:  Giuseppe Filardo; Elizaveta Kon; Francesco Perdisa; Federica Balboni; Maurilio Marcacci
Journal:  Int Orthop       Date:  2014-03-25       Impact factor: 3.075

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