Literature DB >> 19025945

Regional right ventricular function and timing of contraction in healthy volunteers evaluated by strain-encoded MRI.

Ashraf Hamdan1, Thomas Thouet, Sebastian Kelle, Kelle Sebastian, Ingo Paetsch, Rolf Gebker, Ernst Wellnhofer, Bernhard Schnackenburg, Ahmed S Fahmy, Nael F Osman, Eckart Fleck.   

Abstract

PURPOSE: To prospectively determine the feasibility and accuracy of strain-encoded (SENC) magnetic resonance imaging (MRI) for the characterization of the right ventricular free wall (RVFW) strain and timing of contraction at 3.0 Tesla (3T) MRI.
MATERIALS AND METHODS: In 12 healthy volunteers the RVFW was divided into three segments (anterior, lateral, and inferior) in each of three short-axis (SA) slices (apical, mid, and basal) and into three segments (apical, mid, and basal) in a four-chamber view. The study was repeated on a different day and interobserver and interstudy agreements were evaluated.
RESULTS: Maximal systolic longitudinal strain values were highest at the apex and base, with a pronounced decrease in the medial segments (apex: -19.1% +/- 1.4; mid: -17.4% +/- 2; base: -19.4% +/- 2.4, P < 0.001), and maximal systolic circumferential strain showed the highest values at the apex (apex: -18.1% +/- 1.7; mid: -17.6% +/- 1.2; base: -16.6% +/- 0.9, P < 0.001). Peak systolic longitudinal and circumferential shortening occurred earliest at the apex compared to the mid-ventricle and base. Excellent interobserver and interstudy correlation and agreement were observed.
CONCLUSION: The use of SENC MRI for the assessment of normal RV contraction pattern is feasible and accurate in 3T MRI. (c) 2008 Wiley-Liss, Inc.

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Year:  2008        PMID: 19025945     DOI: 10.1002/jmri.21526

Source DB:  PubMed          Journal:  J Magn Reson Imaging        ISSN: 1053-1807            Impact factor:   4.813


  14 in total

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