OBJECTIVE: This study examined whether the association between cortisol secretion and changes in physical health symptoms would depend on other factors in a person's life. The authors expected that physical health effects would emerge particularly when cortisol disturbances co-occur in the context of high levels of trait negative affect or poor sleep. DESIGN: Physical symptoms, diurnal cortisol secretion, affective tendencies, and sleep efficiency were assessed in a 2-yr longitudinal study of 184 older adults. MAIN OUTCOME MEASURE: Two-year changes in physical symptoms. RESULTS: High cortisol levels were associated with increases in physical symptoms, but only among participants who experienced high negative affect and poor sleep. CONCLUSION: Elevated levels of cortisol secretion contribute to older adults' physical symptoms if they co-occur in the context of other emotional and behavioral problems. By contrast, cortisol disturbances may not influence physical symptoms among people who are emotionally well or engage in efficient sleep behaviors.
OBJECTIVE: This study examined whether the association between cortisol secretion and changes in physical health symptoms would depend on other factors in a person's life. The authors expected that physical health effects would emerge particularly when cortisol disturbances co-occur in the context of high levels of trait negative affect or poor sleep. DESIGN: Physical symptoms, diurnal cortisol secretion, affective tendencies, and sleep efficiency were assessed in a 2-yr longitudinal study of 184 older adults. MAIN OUTCOME MEASURE: Two-year changes in physical symptoms. RESULTS: High cortisol levels were associated with increases in physical symptoms, but only among participants who experienced high negative affect and poor sleep. CONCLUSION: Elevated levels of cortisol secretion contribute to older adults' physical symptoms if they co-occur in the context of other emotional and behavioral problems. By contrast, cortisol disturbances may not influence physical symptoms among people who are emotionally well or engage in efficient sleep behaviors.
Authors: Elizabeth J Mezick; Karen A Matthews; Martica Hall; Thomas W Kamarck; Daniel J Buysse; Jane F Owens; Steven E Reis Journal: Psychoneuroendocrinology Date: 2009-05-17 Impact factor: 4.905