Literature DB >> 19024217

Parotid glands tumours: overview of a 10-year experience with 282 patients, focusing on 231 benign epithelial neoplasms.

C Ungari1, F Paparo, W Colangeli, G Iannetti.   

Abstract

Salivary gland tumours are uncommon, representing less than 6% of head and neck neoplasm. Pleomorphic adenoma is the most common benign epithelial salivary gland neoplasm, comprising 50%-74% of all parotid tumours. It is followed by Warthin's tumour (4-14%). The authors retrospectively reviewed 282 eligible patients surgically treated for parotid gland tumours in the last 10 years, focusing on 231 benign epithelial neoplasms. Clinical and diagnostic findings, surgical treatment and surgical outcome were discussed. The diagnosis of a parotid gland neoplasm must be considered in any patient presenting with a lump near the mandible. Smoking habit is important in Warthin's tumour pathogenesis. Fine needle aspiration citology (FNAC) can't lead alone to histological diagnosis. Only surgery can give histological certainty of benignity, thus preventing malignant degeneration, lump infection or risk of size-dependent surgical complications. Conservative formal parotidectomy appears to be the treatment of choice. Tumour pseudopodia and capsule ruptures are recognised factors involved in pleomorphic adenoma recurrences but also tumour multicentricity might play an important role.

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Year:  2008        PMID: 19024217

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  6 in total

1.  An Overview of Parotidectomy for Benign Parotid Lesions with Special Reference to Perioperative Techniques to Avoid Complications: Our Experience.

Authors:  Tripti Maithani; Apoorva Kumar Pandey; Alok Kumar Agrahari
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2018-02-02

2.  Facial extention of ear pathology: infected cholesteatoma causing a parotid abscess.

Authors:  Chrysostomos Tornari; Surojit Pal; Ravi Kumar Lingam; Ali Kalan
Journal:  BMJ Case Rep       Date:  2015-03-20

3.  Pleomorphic adenoma presenting as retroauricular mass: an unusual case.

Authors:  Laina Ndapewa Angula; Le Sun; Ning Fang; Xin Wang
Journal:  Pan Afr Med J       Date:  2020-11-02

4.  Immunohistochemical Expression of p53 in Pleomorphic Adenoma and Carcinoma Ex Pleomorphic Adenoma.

Authors:  Bassel Tarakji; Omar Kujan; Mohammad Z Nassani
Journal:  J Cancer Epidemiol       Date:  2010-12-28

5.  Long-term Follow-up after Extracapsular Dissection of Parotid Pleomorphic Adenomas - A Retrospective Study.

Authors:  Walter Colangeli; Valerio Facchini; Aleksandr Kapitonov; Fabrizio Bozza; Roberto Becelli
Journal:  Ann Maxillofac Surg       Date:  2022-02-01

6.  The Justy mutant mouse strain produces a spontaneous murine model of salivary gland cancer with myoepithelial and basal cell differentiation.

Authors:  Andrean L Simons; Ping Lu; Katherine N Gibson-Corley; Robert A Robinson; David K Meyerholz; John D Colgan
Journal:  Lab Invest       Date:  2013-04-22       Impact factor: 5.662

  6 in total

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