Literature DB >> 19023908

Bench and bedside advances in otitis media.

Joseph E Kerschner1.   

Abstract

PURPOSE OF REVIEW: Otitis media continues to be an important pediatric illness and requires significant expenditures in management and treatment. Despite its prevalence and importance, clinicians often have significant knowledge deficits regarding the most up-to-date research or clinical thinking regarding this disease. The present review aims to discuss recent and important publications related to otitis media and present an analysis of some of these findings. RECENT
FINDINGS: Major basic science and clinical themes related to otitis media are discussed and include the importance of biofilms in otitis media pathogenesis, the evidence that otitis media with effusion impacts development, the impact of otitis media treatment on quality of life, risk factors associated with otitis media and current concepts with respect to vaccine strategies and otitis media.
SUMMARY: Important basic and clinical research in the field of otitis media continues to clarify our understanding of the pathogenesis of this disease and drive new paradigms in treatment and clinical management.

Entities:  

Mesh:

Year:  2008        PMID: 19023908      PMCID: PMC4122517          DOI: 10.1097/moo.0b013e328318448c

Source DB:  PubMed          Journal:  Curr Opin Otolaryngol Head Neck Surg        ISSN: 1068-9508            Impact factor:   2.064


  30 in total

1.  Tympanostomy tubes and developmental outcomes at 9 to 11 years of age.

Authors:  Jack L Paradise; Heidi M Feldman; Thomas F Campbell; Christine A Dollaghan; Howard E Rockette; Dayna L Pitcairn; Clyde G Smith; D Kathleen Colborn; Beverly S Bernard; Marcia Kurs-Lasky; Janine E Janosky; Diane L Sabo; Rollanda E O'Connor; William E Pelham
Journal:  N Engl J Med       Date:  2007-01-18       Impact factor: 91.245

2.  Evolving microbiology and molecular epidemiology of acute otitis media in the pneumococcal conjugate vaccine era.

Authors:  Michael E Pichichero; Janet R Casey
Journal:  Pediatr Infect Dis J       Date:  2007-10       Impact factor: 2.129

3.  Physico-chemical characterisation and immunogenicity of a multi-valent candidate vaccine against non-typeable Haemophilus influenzae and Moraxella catarrhalis.

Authors:  Fatme Mawas; Mei Mei Ho; Rachel Huskisson; Manolya Saydam; Michael J Corbel
Journal:  Vaccine       Date:  2007-04-25       Impact factor: 3.641

4.  Association of proinflammatory cytokine gene polymorphisms with susceptibility to otitis media.

Authors:  Janak A Patel; Sangeeta Nair; Krystal Revai; James Grady; Kokab Saeed; Reuben Matalon; Stan Block; Tasnee Chonmaitree
Journal:  Pediatrics       Date:  2006-12       Impact factor: 7.124

5.  Live attenuated versus inactivated influenza vaccine in infants and young children.

Authors:  Robert B Belshe; Kathryn M Edwards; Timo Vesikari; Steven V Black; Robert E Walker; Micki Hultquist; George Kemble; Edward M Connor
Journal:  N Engl J Med       Date:  2007-02-15       Impact factor: 91.245

6.  Disease severity in patients referred to pediatric otolaryngologists with a diagnosis of otitis media.

Authors:  David M Poetker; Matthew L Ubell; Joseph E Kerschner
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2005-08-24       Impact factor: 1.675

Review 7.  Genetic susceptibility to otitis media.

Authors:  Margaretha L Casselbrant; Ellen M Mandel
Journal:  Curr Opin Allergy Clin Immunol       Date:  2005-02

8.  Genetic polymorphisms in immunoresponse genes TNFA, IL6, IL10, and TLR4 are associated with recurrent acute otitis media.

Authors:  Marieke Emonts; Reinier H Veenhoven; Selma P Wiertsema; Jeanine J Houwing-Duistermaat; Vanessa Walraven; Ronald de Groot; Peter W M Hermans; Elisabeth A M Sanders
Journal:  Pediatrics       Date:  2007-10       Impact factor: 7.124

9.  Quality of life outcomes after ventilating tube insertion for otitis media in an Australian population.

Authors:  Yan Chow; David A M Wabnitz; John Ling
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2007-07-23       Impact factor: 1.675

10.  Association of the FBXO11 gene with chronic otitis media with effusion and recurrent otitis media: the Minnesota COME/ROM Family Study.

Authors:  Fernando Segade; Kathleen A Daly; Dax Allred; Pamela J Hicks; Miranda Cox; Mark Brown; Rachel E Hardisty-Hughes; Steve D M Brown; Stephen S Rich; Donald W Bowden
Journal:  Arch Otolaryngol Head Neck Surg       Date:  2006-07
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  1 in total

1.  Differential response of gel-forming mucins to pathogenic middle ear bacteria.

Authors:  Joseph E Kerschner; Wenzhou Hong; Pawjai Khampang; Nikki Johnston
Journal:  Int J Pediatr Otorhinolaryngol       Date:  2014-06-06       Impact factor: 1.675

  1 in total

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