C Jansen1, P Ringleb, D Böckler, M Hartmann, W Hacke. 1. Neurologische Klinik, Klinikum der Ruprecht-Karls-Universität, Im Neuenheimer Feld 400, 69120, Heidelberg. claudia.jansen@med.uni-heidelberg.de
Abstract
BACKGROUND: This prospective, controlled, randomised study evaluates differences concerning cognitive functions between carotid endarterectomy (CEA) and stent-protected angioplasty (CAS) as a treatment for symptomatic carotid stenosis. Both techniques include risks whose effect on neuropsychological abilities remains yet unknown. METHODS:Twenty-seven patients suffering from high-grade symptomatic carotid stenosis underwent neuropsychological testing before, 1 month, and 6 months after treatment. After the first testing patients were randomly assigned for CEA (n=10) or CAS (n=17) as treatment. The patients' cognitive functions were compared to those of 13 healthy controls. RESULTS: Whether patients underwent CEA or CAS made no difference in the neuropsychological outcome 4 weeks and 6 months after treatment. Patients always performed worse than the healthy controls. CONCLUSION: Both techniques seem to have no different effect on cognitive functions.
RCT Entities:
BACKGROUND: This prospective, controlled, randomised study evaluates differences concerning cognitive functions between carotid endarterectomy (CEA) and stent-protected angioplasty (CAS) as a treatment for symptomatic carotid stenosis. Both techniques include risks whose effect on neuropsychological abilities remains yet unknown. METHODS: Twenty-seven patients suffering from high-grade symptomatic carotid stenosis underwent neuropsychological testing before, 1 month, and 6 months after treatment. After the first testing patients were randomly assigned for CEA (n=10) or CAS (n=17) as treatment. The patients' cognitive functions were compared to those of 13 healthy controls. RESULTS: Whether patients underwent CEA or CAS made no difference in the neuropsychological outcome 4 weeks and 6 months after treatment. Patients always performed worse than the healthy controls. CONCLUSION: Both techniques seem to have no different effect on cognitive functions.
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