Literature DB >> 1901831

Clonal analysis of the relationship between class II MHC-restricted cytolysis and lymphokine secretion in murine L3T4+ T cells.

X M Gao1, F Y Liew, K Bottomly, A Meager, J P Tite.   

Abstract

A panel of peptide-specific murine CD4+ T-cell clones was tested for lymphokine secretion, antigen-specific cytolysis and CD3-mediated cytolysis. The data indicated an imperfect correlation between Th1/Th2 status with regard to antigen-specific cytolysis but also indicated that all the clones were cytotoxic when stimulated with anti-CD3 antibody.

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Year:  1991        PMID: 1901831      PMCID: PMC1384493     

Source DB:  PubMed          Journal:  Immunology        ISSN: 0019-2805            Impact factor:   7.397


  15 in total

Review 1.  Heterogeneity of cytokine secretion patterns and functions of helper T cells.

Authors:  T R Mosmann; R L Coffman
Journal:  Adv Immunol       Date:  1989       Impact factor: 3.543

2.  Translation of mRNAs for subunits of chloroplast coupling factor 1 in spinach.

Authors:  A Watanabe; C A Price
Journal:  Proc Natl Acad Sci U S A       Date:  1982-10       Impact factor: 11.205

3.  Therapy with monoclonal antibodies by elimination of T-cell subsets in vivo.

Authors:  S P Cobbold; A Jayasuriya; A Nash; T D Prospero; H Waldmann
Journal:  Nature       Date:  1984 Dec 6-12       Impact factor: 49.962

Review 4.  A functional dichotomy in CD4+ T lymphocytes.

Authors:  K Bottomly
Journal:  Immunol Today       Date:  1988-09

5.  Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

Authors:  D P Dialynas; Z S Quan; K A Wall; A Pierres; J Quintáns; M R Loken; M Pierres; F W Fitch
Journal:  J Immunol       Date:  1983-11       Impact factor: 5.422

6.  Monoclonal antibodies to murine CD3 epsilon define distinct epitopes, one of which may interact with CD4 during T cell activation.

Authors:  P Portoles; J Rojo; A Golby; M Bonneville; S Gromkowski; L Greenbaum; C A Janeway; D B Murphy; K Bottomly
Journal:  J Immunol       Date:  1989-06-15       Impact factor: 5.422

7.  Production of a monoclonal antibody to and molecular characterization of B-cell stimulatory factor-1.

Authors:  J Ohara; W E Paul
Journal:  Nature       Date:  1985 May 23-29       Impact factor: 49.962

8.  A monoclonal antibody to murine CD45R distinguishes CD4 T cell populations that produce different cytokines.

Authors:  K Bottomly; M Luqman; L Greenbaum; S Carding; J West; T Pasqualini; D B Murphy
Journal:  Eur J Immunol       Date:  1989-04       Impact factor: 5.532

9.  Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins.

Authors:  T R Mosmann; H Cherwinski; M W Bond; M A Giedlin; R L Coffman
Journal:  J Immunol       Date:  1986-04-01       Impact factor: 5.422

10.  Cytolytic activity of Ia-restricted T cell clones and hybridomas: evidence for a cytolytic mechanism independent of interferon-gamma, lymphotoxin, and tumor necrosis factor-alpha.

Authors:  S T Ju; P Strack; D Stromquist; R H Dekruyff
Journal:  Cell Immunol       Date:  1988-12       Impact factor: 4.868

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  3 in total

1.  Major histocompatibility complex class II-restricted cytotoxicity by self-myelin basic protein-reactive T-cell hybridomas: evidence for a tumour necrosis factor-independent nucleolytic mechanism.

Authors:  D C Rayner; L D Petrycky-Cox; M Diocee; E Rector
Journal:  Immunology       Date:  1993-02       Impact factor: 7.397

2.  Influence of the antigen delivery system on immunoglobulin isotype selection and cytokine production in response to influenza A nucleoprotein.

Authors:  S J Brett; L Dunlop; F Y Liew; J P Tite
Journal:  Immunology       Date:  1993-10       Impact factor: 7.397

3.  TNF-alpha reverses the disease-exacerbating effect of subcutaneous immunization against murine cutaneous leishmaniasis.

Authors:  F Y Liew; Y Li; D M Yang; A Severn; F E Cox
Journal:  Immunology       Date:  1991-10       Impact factor: 7.397

  3 in total

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