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Literature DB >> 19017614

Adipocyte metabolism and obesity.

Abstract

Adipose tissue metabolism exerts a profound impact on whole-body metabolism. We review how fuel partitioning between adipocytes and other tissues affects insulin signaling pathways. We discuss the role of adipose tissue inflammation in adipocyte metabolism and whole-body insulin sensitivity. Finally, we mention the role of adipokines in autocrine and paracrine signaling.

Entities: Disease Gene

Mesh：

Year: 2008 PMID： 19017614 PMCID： PMC2674728 DOI： 10.1194/jlr.R800057-JLR200

Source DB: PubMed Journal: J Lipid Res ISSN： 0022-2275 Impact factor: 5.922

35 in total

1. Beneficial effects of subcutaneous fat transplantation on metabolism.

Authors: Thien T Tran; Yuji Yamamoto; Stephane Gesta; C Ronald Kahn
Journal: Cell Metab Date: 2008-05 Impact factor: 27.287

2. Obesity-associated improvements in metabolic profile through expansion of adipose tissue.

Authors: Ja-Young Kim; Esther van de Wall; Mathieu Laplante; Anthony Azzara; Maria E Trujillo; Susanna M Hofmann; Todd Schraw; Jorge L Durand; Hua Li; Guangyu Li; Linda A Jelicks; Mark F Mehler; David Y Hui; Yves Deshaies; Gerald I Shulman; Gary J Schwartz; Philipp E Scherer
Journal: J Clin Invest Date: 2007-09 Impact factor: 14.808

3. Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.

Authors: Pengxiang She; Cynthia Van Horn; Tanya Reid; Susan M Hutson; Robert N Cooney; Christopher J Lynch
Journal: Am J Physiol Endocrinol Metab Date: 2007-10-09 Impact factor: 4.310

4. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation.

Authors: Naomi Hosogai; Atsunori Fukuhara; Kazuya Oshima; Yugo Miyata; Sachiyo Tanaka; Katsumori Segawa; Shigetada Furukawa; Yoshihiro Tochino; Ryutaro Komuro; Morihiro Matsuda; Iichiro Shimomura
Journal: Diabetes Date: 2007-04 Impact factor: 9.461

5. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice.

Authors: Jianping Ye; Zhanguo Gao; Jun Yin; Qing He
Journal: Am J Physiol Endocrinol Metab Date: 2007-07-31 Impact factor: 4.310

Review 6. The physiological and molecular regulation of lipoprotein assembly and secretion.

Authors: Daniel A Blasiole; Roger A Davis; Alan D Attie
Journal: Mol Biosyst Date: 2007-07-16

7. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.

Authors: Mara Monetti; Malin C Levin; Matthew J Watt; Mini P Sajan; Stephen Marmor; Brian K Hubbard; Robert D Stevens; James R Bain; Christopher B Newgard; Robert V Farese; Andrea L Hevener; Robert V Farese
Journal: Cell Metab Date: 2007-07 Impact factor: 27.287

Review 8. Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease.

Authors: Margaret F Gregor; Gökhan S Hotamisligil
Journal: J Lipid Res Date: 2007-05-09 Impact factor: 5.922

Review 9. Inflammation and insulin resistance.

Authors: Carl de Luca; Jerrold M Olefsky
Journal: FEBS Lett Date: 2007-11-29 Impact factor: 4.124

10. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.

Authors: Alexander V Chibalin; Ying Leng; Elaine Vieira; Anna Krook; Marie Björnholm; Yun Chau Long; Olga Kotova; Zhihui Zhong; Fumio Sakane; Tatiana Steiler; Carolina Nylén; Jianjun Wang; Markku Laakso; Matthew K Topham; Marc Gilbert; Harriet Wallberg-Henriksson; Juleen R Zierath
Journal: Cell Date: 2008-02-08 Impact factor: 41.582

71 in total

Adipocyte metabolism and obesity.

1. Beneficial effects of subcutaneous fat transplantation on metabolism.

2. Obesity-associated improvements in metabolic profile through expansion of adipose tissue.

3. Obesity-related elevations in plasma leucine are associated with alterations in enzymes involved in branched-chain amino acid metabolism.

4. Adipose tissue hypoxia in obesity and its impact on adipocytokine dysregulation.

5. Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice.

Review 6. The physiological and molecular regulation of lipoprotein assembly and secretion.

7. Dissociation of hepatic steatosis and insulin resistance in mice overexpressing DGAT in the liver.

Review 8. Thematic review series: Adipocyte Biology. Adipocyte stress: the endoplasmic reticulum and metabolic disease.

Review 9. Inflammation and insulin resistance.

10. Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.

Review 1. Adipose tissue remodeling and obesity.

2. The ubiquitin ligase Fbxw7 controls adipocyte differentiation by targeting C/EBPalpha for degradation.

3. Perirenal Adiposity is Associated With Lower Progression-Free Survival From Ovarian Cancer.

Review 4. Short sleep and circulating adipokine concentrations: does the fat hit the fire?

Review 5. Adipose tissue, diabetes and Chagas disease.

6. Common Inflammatory Markers in Polycystic Ovary Syndrome (PCOS): A BMI (Body Mass Index)-Matched Case-Control Study.

Review 7. Insulin resistance and the polycystic ovary syndrome revisited: an update on mechanisms and implications.

8. Lipocalin-2 deficiency impairs thermogenesis and potentiates diet-induced insulin resistance in mice.

9. Inflammation, a link between obesity and cardiovascular disease.

10. Perspectives on adipose tissue, chagas disease and implications for the metabolic syndrome.