Literature DB >> 19017378

Aplastic anemia induced disc edema and visual loss in pregnancy: a case report.

Shailesh K Gupta1, Vikram S Brar, Ravi Keshavamurthy, Kakarla V Chalam.   

Abstract

INTRODUCTION: A case of aplastic anemia diagnosed during pregnancy, which developed bilateral disc edema and acute pre-retinal hemorrhage leading to vision loss. CASE
PRESENTATION: A 20 year old primagravid female developed acute vision loss in her right eye, during hospitalization for treatment of aplastic anemia diagnosed during her pregnancy. Her best-corrected visual acuity (BCVA) was hand motions and fundus evaluation revealed a large pre-macular hemorrhage in the right eye (OD) and bilateral disc edema. Neuro-imaging studies did not reveal any signs of intracranial mass lesion or edema.
CONCLUSION: There was resolution of the disc edema with improvement in the pre-macular hemorrhage resulting in 20/50 vision in the right eye, following supportive transfusions. Ophthalmic manifestations developing in a pregnant patient with aplastic anemia can be successfully managed with supportive care including red blood cell and platelet transfusions.

Entities:  

Year:  2008        PMID: 19017378      PMCID: PMC2611979          DOI: 10.1186/1757-1626-1-322

Source DB:  PubMed          Journal:  Cases J        ISSN: 1757-1626


  9 in total

1.  Pseudotumor cerebri in two adolescents with acquired aplastic anemia.

Authors:  Michael R Jeng; Martha Rieman; Manoo Bhakta; Kathleen Helton; Winfred C Wang
Journal:  J Pediatr Hematol Oncol       Date:  2002-12       Impact factor: 1.289

2.  Pseudotumor cerebri in idiopathic aplastic anemia.

Authors:  Sayeda Asad Nazir; R Michael Siatkowski
Journal:  J AAPOS       Date:  2003-02       Impact factor: 1.220

Review 3.  Pregnancy-associated hypoplastic anemia: a review.

Authors:  T E Snyder; L P Lee; S Lynch
Journal:  Obstet Gynecol Surv       Date:  1991-05       Impact factor: 2.347

4.  Ocular findings in aplastic anemia.

Authors:  A M Mansour; H I Salti; D P Han; A Khoury; S M Friedman; Z Salem; K Ibrahim; A Bazerbachi; N Saghir
Journal:  Ophthalmologica       Date:  2000       Impact factor: 3.250

5.  Prevalence of retinopathy in patients with anemia or thrombocytopenia.

Authors:  M C Carraro; L Rossetti; G C Gerli
Journal:  Eur J Haematol       Date:  2001-10       Impact factor: 2.997

Review 6.  Pathophysiologic mechanisms in acquired aplastic anemia.

Authors:  Neal S Young
Journal:  Hematology Am Soc Hematol Educ Program       Date:  2006

7.  Recurrent transient bone marrow hypoplasia associated with pregnancy.

Authors:  E Cohen; Y Ilan; S Gillis; E J Dann; E A Rachmilewitz
Journal:  Acta Haematol       Date:  1993       Impact factor: 2.195

Review 8.  Pregnancy associated aplastic anemia--a series of 10 cases with review of literature.

Authors:  V P Choudhry; Sunil Gupta; Meenal Gupta; Rajesh Kashyap; R Saxena
Journal:  Hematology       Date:  2002-08       Impact factor: 2.269

Review 9.  Anemia and papilledema.

Authors:  Valérie Biousse; Janet C Rucker; Catherine Vignal; Isabelle Crassard; Bradley J Katz; Nancy J Newman
Journal:  Am J Ophthalmol       Date:  2003-04       Impact factor: 5.258

  9 in total
  1 in total

Review 1.  Ocular manifestations of idiopathic aplastic anemia: retrospective study and literature review.

Authors:  Ahmad M Mansour; Jong Wook Lee; Seung Ah Yahng; Kyu Seop Kim; Maha Shahin; Nelson Hamerschlak; Rubens N Belfort; Shree K Kurup
Journal:  Clin Ophthalmol       Date:  2014-04-17
  1 in total

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