Literature DB >> 1901653

An idiotypic network model of AIDS immunopathogenesis.

G W Hoffmann1, T A Kion, M D Grant.   

Abstract

Considerations from a network theory of the immune system suggest that human immunodeficiency virus and allogeneic stimuli may act synergistically to cause AIDS. The immune responses to these stimuli include two components that are directed against each other. In some AIDS risk groups other antigens that mimic major histocompatibility complex antigens may substitute for allogeneic stimuli. Implications for the prevention of AIDS are discussed.

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Year:  1991        PMID： 1901653      PMCID： PMC51384          DOI： 10.1073/pnas.88.8.3060

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  44 in total

1.  Autoantibodies to type II collagen: occurrence in rheumatoid arthritis, other arthritides, autoimmune connective tissue diseases, and chronic inflammatory syndromes.

Authors:  E K Choi; P A Gatenby; N W McGill; J F Bateman; W G Cole; J R York
Journal:  Ann Rheum Dis       Date:  1988-04       Impact factor: 19.103

2.  HIV-gp120 can block CD4-class II MHC-mediated adhesion.

Authors:  Y Rosenstein; S J Burakoff; S H Herrmann
Journal:  J Immunol       Date:  1990-01-15       Impact factor: 5.422

Review 3.  AIDS: non-infectious deficiencies acquired by drug consumption and other risk factors.

Authors:  P H Duesberg
Journal:  Res Immunol       Date:  1990-01

4.  Major histocompatibility complex-linked and T cell-dependent selection of antibody repertoires. Quantitation of I-E-related specificities in normal mice.

Authors:  C Peña Rossi; P Pereira; D Portnoï; A Coutinho
Journal:  Eur J Immunol       Date:  1989-10       Impact factor: 5.532

5.  HIV and HLA similarity.

Authors:  J A Young
Journal:  Nature       Date:  1988-05-19       Impact factor: 49.962

Review 6.  Immunological consequences of HIV infection: advantage of being low responder casts doubts on vaccine development.

Authors:  C Martínez-A; M A Marcos; A de la Hera; C Marquez; J M Alonso; M L Toribio; A Coutinho
Journal:  Lancet       Date:  1988-02-27       Impact factor: 79.321

7.  AIDS and related syndromes as a viral-induced autoimmune disease of the immune system: an anti-MHC II disorder. Therapeutic implications.

Authors:  J M Andrieu; P Even; A Venet
Journal:  AIDS Res       Date:  1986

8.  A new symmetry: A anti-B is anti-(B anti-A), and reverse enhancement.

Authors:  G W Hoffmann; A Cooper-Willis; M Chow
Journal:  J Immunol       Date:  1986-07-01       Impact factor: 5.422

9.  Patterns of autoreactivity to collagen type II in autoimmune MRL/l mice.

Authors:  A Tarkowski; R Holmdahl; K Rubin; L Klareskog; L A Nilsson; K Gunnarsson
Journal:  Clin Exp Immunol       Date:  1986-02       Impact factor: 4.330

Review 10.  Rheumatologic manifestations of infection with human immunodeficiency virus (HIV).

Authors:  B R Kaye
Journal:  Ann Intern Med       Date:  1989-07-15       Impact factor: 25.391
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  17 in total

1.  A gp120 HIV peptide with high similarity to HLA class II beta chains enhances PPD-specific and autoreactive T cell activation.

Authors:  O Pugliese; M Viora; B Camponeschi; P Cordiali Fei; F Caprilli; A Chersi; M Evangelista; A M Di Massimo; V Colizzi
Journal:  Clin Exp Immunol       Date:  1992-11       Impact factor: 4.330

2.  Looking beyond the numbers.

Authors:  S Wolf
Journal:  Integr Physiol Behav Sci       Date:  1992 Apr-Jun

Review 3.  Molecular immunopathogenesis of HIV infection.

Authors:  T T Ng; A J Pinching; C Guntermann; W J Morrow
Journal:  Genitourin Med       Date:  1996-12

4.  Relationship of antibodies against CD4+ T cells in HIV-infected patients to markers of activation and progression: autoantibodies are closely associated with CD4 cell depletion.

Authors:  C Müller; S Kukel; R Bauer
Journal:  Immunology       Date:  1993-06       Impact factor: 7.397

5.  The nature of the autoimmune antibody repertoire in human immunodeficiency virus type 1 infection.

Authors:  H J Ditzel; S M Barbas; C F Barbas; D R Burton
Journal:  Proc Natl Acad Sci U S A       Date:  1994-04-26       Impact factor: 11.205

6.  Molecular mimicry between the human immunodeficiency virus type 1 gp120 V3 loop and human brain proteins.

Authors:  J R Trujillo; M F McLane; T H Lee; M Essex
Journal:  J Virol       Date:  1993-12       Impact factor: 5.103

7.  Anti-lymphocyte antibodies in plasma of HIV-1-infected patients preferentially react with MHC class II-negative T cells and are linked to antibodies against gp41.

Authors:  C Müller; S Kukel; K E Schneweis; R Bauer
Journal:  Clin Exp Immunol       Date:  1994-09       Impact factor: 4.330

8.  Rates of amino acid change in the envelope protein correlate with pathogenicity of primate lentiviruses.

Authors:  E G Shpaer; J I Mullins
Journal:  J Mol Evol       Date:  1993-07       Impact factor: 2.395

9.  Raised levels of tumour necrosis factor-alpha and neopterin, but not interferon-alpha, in serum of HIV-1-infected patients from Ethiopia.

Authors:  S Ayehunie; A Sonnerborg; T Yemane-Berhan; D W Zewdie; S Britton; O Strannegard
Journal:  Clin Exp Immunol       Date:  1993-01       Impact factor: 4.330

10.  Human immunodeficiency virus (HIV) nef-specific cytotoxic T lymphocytes in noninfected heterosexual contact of HIV-infected patients.

Authors:  P Langlade-Demoyen; N Ngo-Giang-Huong; F Ferchal; E Oksenhendler
Journal:  J Clin Invest       Date:  1994-03       Impact factor: 14.808
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