Literature DB >> 19016284

Reduction of Alzheimer's disease amyloid plaque load in transgenic mice by D3, A D-enantiomeric peptide identified by mirror image phage display.

Thomas van Groen1, Katja Wiesehan, Susanne A Funke, Inga Kadish, Luitgard Nagel-Steger, Dieter Willbold.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19016284     DOI： 10.1002/cmdc.200800273

Source DB:  PubMed          Journal:  ChemMedChem        ISSN： 1860-7179            Impact factor:   3.466


× No keyword cloud information.
  37 in total

1.  Oral treatment with the d-enantiomeric peptide D3 improves the pathology and behavior of Alzheimer's Disease transgenic mice.

Authors:  Susanne Aileen Funke; Thomas van Groen; Inga Kadish; Dirk Bartnik; Luitgard Nagel-Steger; Oleksandr Brener; Torsten Sehl; Renu Batra-Safferling; Christine Moriscot; Guy Schoehn; Anselm H C Horn; Andreas Müller-Schiffmann; Carsten Korth; Heinrich Sticht; Dieter Willbold
Journal:  ACS Chem Neurosci       Date:  2010-08-02       Impact factor: 4.418

2.  Treatment with D3 removes amyloid deposits, reduces inflammation, and improves cognition in aged AβPP/PS1 double transgenic mice.

Authors:  Thomas van Groen; Inga Kadish; Susanne Aileen Funke; Dirk Bartnik; Dieter Willbold
Journal:  J Alzheimers Dis       Date:  2013       Impact factor: 4.472

3.  A d-enantiomeric peptide interferes with heteroassociation of amyloid-β oligomers and prion protein.

Authors:  Nadine S Rösener; Lothar Gremer; Elke Reinartz; Anna König; Oleksandr Brener; Henrike Heise; Wolfgang Hoyer; Philipp Neudecker; Dieter Willbold
Journal:  J Biol Chem       Date:  2018-08-21       Impact factor: 5.157

4.  The effect of retro-inverse D-amino acid Aβ-peptides on Aβ-fibril formation.

Authors:  Wenhui Xi; Ulrich H E Hansmann
Journal:  J Chem Phys       Date:  2019-03-07       Impact factor: 3.488

5.  D-peptide inhibitors of the p53-MDM2 interaction for targeted molecular therapy of malignant neoplasms.

Authors:  Min Liu; Chong Li; Marzena Pazgier; Changqing Li; Yubin Mao; Yifan Lv; Bing Gu; Gang Wei; Weirong Yuan; Changyou Zhan; Wei-Yue Lu; Wuyuan Lu
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-26       Impact factor: 11.205

6.  Pharmacokinetic Properties of a Novel D-Peptide Developed to be Therapeutically Active Against Toxic β-Amyloid Oligomers.

Authors:  Leonie H E Leithold; Nan Jiang; Julia Post; Tamar Ziehm; Elena Schartmann; Janine Kutzsche; N Jon Shah; Jörg Breitkreutz; Karl-Josef Langen; Antje Willuweit; Dieter Willbold
Journal:  Pharm Res       Date:  2015-09-17       Impact factor: 4.200

7.  A Hendecad Motif Is Preferred for Heterochiral Coiled-Coil Formation.

Authors:  Dale F Kreitler; Zhihui Yao; Jay D Steinkruger; David E Mortenson; Lijun Huang; Ritesh Mittal; Benjamin R Travis; Katrina T Forest; Samuel H Gellman
Journal:  J Am Chem Soc       Date:  2019-01-15       Impact factor: 15.419

Review 8.  Mirror image proteins.

Authors:  Le Zhao; Wuyuan Lu
Journal:  Curr Opin Chem Biol       Date:  2014-10-01       Impact factor: 8.822

9.  Validation and Characterization of a Novel Peptide That Binds Monomeric and Aggregated β-Amyloid and Inhibits the Formation of Neurotoxic Oligomers.

Authors:  Renae K Barr; Giuseppe Verdile; Linda K Wijaya; Michael Morici; Kevin Taddei; Veer B Gupta; Steve Pedrini; Liang Jin; Joseph A Nicolazzo; Erin Knock; Paul E Fraser; Ralph N Martins
Journal:  J Biol Chem       Date:  2015-11-04       Impact factor: 5.157

10.  In Vitro and In Vivo Efficacies of the Linear and the Cyclic Version of an All-d-Enantiomeric Peptide Developed for the Treatment of Alzheimer's Disease.

Authors:  Sarah Schemmert; Luana Cristina Camargo; Dominik Honold; Ian Gering; Janine Kutzsche; Antje Willuweit; Dieter Willbold
Journal:  Int J Mol Sci       Date:  2021-06-18       Impact factor: 5.923
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.