Literature DB >> 19015925

Disparities in reported reasons for not initiating or stopping antiretroviral treatment among a diverse sample of persons living with HIV.

Mallory O Johnson1, Margaret A Chesney, Torsten B Neilands, Samantha E Dilworth, Robert H Remien, Lance S Weinhardt, F Lennie Wong, Stephen F Morin.   

Abstract

BACKGROUND: Disparities in the use of antiretroviral therapy (ART) for HIV disease have been documented across race, gender, and substance use groups.
OBJECTIVE: The current analysis compares self-reported reasons for never taking or stopping ART among a diverse sample of men and women living with HIV.
DESIGN: Cross-sectional interview. PARTICIPANTS: HIV + (N = 3,818) adults, 968 of whom reported discontinuing or never using ART. MEASUREMENTS: Computerized self-administered and interviewer-administered self-reported demographic and treatment variables, including gender, race, ethnicity, CD4 count, detectable viral load, and reported reasons for not taking antiretroviral therapy.
RESULTS: Despite equivalent use of ART in the current sample, African-American respondents were 1.7 times more likely to report wanting to hide their HIV status and 1.7 times more likely to report a change in doctors/clinics as reasons for stopping ART (p = .049, and p = .042) and had odds 4.5 times those of non-African Americans of reporting waiting for viral marker counts to worsen (p = < .0001). There was a lower tendency (OR = 0.4) for women to endorse concerns of keeping their HIV status hidden as a reason for stopping ART compared to men (p = .003). Although those with an IDU history were less likely to be on ART, no differences in reasons for stopping or never initiating ART were found between those with and without an IDU history.
CONCLUSIONS: A desire to conceal HIV status as well as a change in doctors/clinics as reasons for discontinuing ART were considerably more common among African Americans, suggesting that perceived HIV/AIDS stigma is an obstacle to maintenance of treatment. Findings also indicate differences in reasons for stopping ART by gender and a perceived desire to wait for counts to worsen as a reason for not taking ART by African Americans, regardless of detectable viral load, CD4 count, age, education, employment, sexual orientation, and site.

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Year:  2008        PMID: 19015925      PMCID: PMC2628985          DOI: 10.1007/s11606-008-0854-z

Source DB:  PubMed          Journal:  J Gen Intern Med        ISSN: 0884-8734            Impact factor:   5.128


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4.  Issues for women with heterosexually transmitted HIV disease.

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Review 9.  A systematic review of interventions to reduce HIV-related stigma and discrimination from 2002 to 2013: how far have we come?

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