Highly conserved segments in mammalian chromosomes.

Mammalian chromosomes from seven species for which gene maps exist were studied by high-resolution techniques to identify areas of conserved chromosome banding homology. High-resolution comparisons of human, chimpanzee, gorilla, orangutan, African green monkey, cat, and mouse chromosomes revealed regions of apparently conserved chromosomal banding, which may indicate the likely positions of conserved linkage in the phylogeny of mammals. This analysis indicates that many regions of subbanding homology may have remained intact during the evolution of mammals and reflects a high degree of chromosome conservation in diverse species.