Literature DB >> 19015131

Genetic association analysis with FAMHAP: a major program update.

Christine Herold1, Tim Becker.   

Abstract

UNLABELLED: FAMHAP is an established software for haplotype association analysis of nuclear families. We have released a major update that comprises various new features for case-control data. Furthermore, weprovide an additional program runFamhap that allows users to start the same method repeatedly for varying sets of genetic markers. In addition, a platform-independent graphical user interface (GUI) was developed to simplify the usage of both FAMHAP and runFamhap. The runFamhap program greatly facilitates the application of FAMHAP to genome-wide association studies (GWAS) and supports flexible genome-wide haplotype analysis. As an example, we describe application to HapMap data. AVAILABILITY: The software is available at http://famhap.meb.uni-bonn.de

Mesh：

Year:  2008        PMID： 19015131     DOI： 10.1093/bioinformatics/btn581

Source DB:  PubMed          Journal:  Bioinformatics        ISSN： 1367-4803            Impact factor:   6.937


  31 in total

1.  Joint analysis of tightly linked SNPs in screening step of genome-wide association studies leads to increased power.

Authors:  Tim Becker; Christine Herold
Journal:  Eur J Hum Genet       Date:  2009-02-18       Impact factor: 4.246

2.  Initial interrogation, confirmation and fine mapping of modifying genes: STAT3, IL1B and IFNGR1 determine cystic fibrosis disease manifestation.

Authors:  Heike Labenski; Silke Hedtfeld; Tim Becker; Burkhard Tümmler; Frauke Stanke
Journal:  Eur J Hum Genet       Date:  2011-07-06       Impact factor: 4.246

3.  Genetic variation on the BAT1-NFKBIL1-LTA region of major histocompatibility complex class III associates with periodontitis.

Authors:  K A Elisa Kallio; Marja Marchesani; Efthymia Vlachopoulou; Päivi Mäntylä; Susanna Paju; Kåre Buhlin; Anna L Suominen; Johanna Contreras; Matti Knuuttila; Marcela Hernandez; Sisko Huumonen; Markku S Nieminen; Markus Perola; Juha Sinisalo; Marja-Liisa Lokki; Pirkko J Pussinen
Journal:  Infect Immun       Date:  2014-02-24       Impact factor: 3.441

4.  Influence of a latrophilin 3 (LPHN3) risk haplotype on event-related potential measures of cognitive response control in attention-deficit hyperactivity disorder (ADHD).

Authors:  Andreas J Fallgatter; Ann-Christine Ehlis; Thomas Dresler; Andreas Reif; Christian P Jacob; Mauricio Arcos-Burgos; Maximilian Muenke; Klaus-Peter Lesch
Journal:  Eur Neuropsychopharmacol       Date:  2012-12-12       Impact factor: 4.600

5.  Differential decay of parent-of-origin-specific genomic sharing in cystic fibrosis-affected sib pairs maps a paternally imprinted locus to 7q34.

Authors:  Frauke Stanke; Colin Davenport; Silke Hedtfeld; Burkhard Tümmler
Journal:  Eur J Hum Genet       Date:  2010-01-06       Impact factor: 4.246

6.  Investigation of a genome wide association signal for obesity: synthetic association and haplotype analyses at the melanocortin 4 receptor gene locus.

Authors:  André Scherag; Ivonne Jarick; Jessica Grothe; Heike Biebermann; Susann Scherag; Anna-Lena Volckmar; Carla Ivane Ganz Vogel; Brandon Greene; Johannes Hebebrand; Anke Hinney
Journal:  PLoS One       Date:  2010-11-15       Impact factor: 3.240

7.  The role of Pannexin gene variants in schizophrenia: systematic analysis of phenotypes.

Authors:  Micha Gawlik; Martin Wagner; Bruno Pfuhlmann; Gerald Stöber
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2015-07-30       Impact factor: 5.270

8.  Hierarchical fine mapping of the cystic fibrosis modifier locus on 19q13 identifies an association with two elements near the genes CEACAM3 and CEACAM6.

Authors:  Frauke Stanke; Tim Becker; Silke Hedtfeld; Stephanie Tamm; Thomas F Wienker; Burkhard Tümmler
Journal:  Hum Genet       Date:  2010-01-03       Impact factor: 4.132

9.  Detecting purely epistatic multi-locus interactions by an omnibus permutation test on ensembles of two-locus analyses.

Authors:  Waranyu Wongseree; Anunchai Assawamakin; Theera Piroonratana; Saravudh Sinsomros; Chanin Limwongse; Nachol Chaiyaratana
Journal:  BMC Bioinformatics       Date:  2009-09-17       Impact factor: 3.169

10.  Association of MMP-2 polymorphisms with severe and very severe COPD: a case control study of MMPs-1, 9 and 12 in a European population.

Authors:  Imran Haq; Sally Chappell; Simon R Johnson; Juzer Lotya; Leslie Daly; Kevin Morgan; Tamar Guetta-Baranes; Josep Roca; Roberto Rabinovich; Ann B Millar; Seamas C Donnelly; Vera Keatings; William MacNee; Jan Stolk; Pieter S Hiemstra; Massimo Miniati; Simonetta Monti; Clare M O'Connor; Noor Kalsheker
Journal:  BMC Med Genet       Date:  2010-01-15       Impact factor: 2.103
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