Literature DB >> 19015076

Treatment experiences of testicular cancer in Hispanic patients with Down's syndrome at the National Cancer Institute of Mexico.

Jose Luis Aguilar-Ponce1, Silvia Vidal-Millán, Carlos Molina-Calzada, Fatima Chilaca-Rosas, Jorge Martínez-Cedillo, Juan Carlos Cruz-López.   

Abstract

We present 4 case studies of patients with Down's syndrome and testicular germ-cell cancer, treated with conventional methods at the National Cancer Institute of Mexico, with similar outcomes as patients without this syndrome. There are several reports of testicular cancer arising in patients with Down's syndrome worldwide, mainly from Caucasian populations. We discuss some theories about the association and the possible increase of incidence.

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Year:  2008        PMID: 19015076     DOI: 10.1007/s12094-008-0286-6

Source DB:  PubMed          Journal:  Clin Transl Oncol        ISSN: 1699-048X            Impact factor:   3.405


  9 in total

1.  Seminoma associated with bilateral cryptorchidism in Down's syndrome: a case report.

Authors:  M Miki; N Ohtake; M Hasumi; M Ohi; S Moriyama
Journal:  Int J Urol       Date:  1999-07       Impact factor: 3.369

2.  Maturation delay of germ cells in fetuses with trisomy 21 results in increased risk for the development of testicular germ cell tumors.

Authors:  Martine Cools; Friedemann Honecker; Hans Stoop; Joris D Veltman; Ronald R de Krijger; Ewout Steyerberg; Katja P Wolffenbuttel; Carsten Bokemeyer; Yun-Fai Chris Lau; Stenvert L S Drop; Leendert H J Looijenga
Journal:  Hum Pathol       Date:  2006-01       Impact factor: 3.466

Review 3.  An excess of testicular germ cell tumors in Down's syndrome: three case reports and a review of the literature.

Authors:  D Satgé; A J Sasco; H Curé; B Leduc; D Sommelet; M J Vekemans
Journal:  Cancer       Date:  1997-09-01       Impact factor: 6.860

4.  Genetic risk factors in tumours of the testis: lessons from twin studies.

Authors:  C B Lambalk; D I Boomsma
Journal:  Twin Res       Date:  1998-09

5.  Challenges in treating patients with Down's syndrome and testicular cancer with chemotherapy and radiotherapy: The Royal Marsden experience.

Authors:  S Hafeez; R A Sharma; R A Huddart; D P Dearnaley; A Horwich
Journal:  Clin Oncol (R Coll Radiol)       Date:  2007-03       Impact factor: 4.126

Review 6.  The 'oestrogen hypothesis'- where do we stand now?

Authors:  Richard M Sharpe
Journal:  Int J Androl       Date:  2003-02

7.  Genetic abnormalities in men with germ cell tumors.

Authors:  F H Dexeus; C J Logothetis; C Chong; A Sella; S Ogden
Journal:  J Urol       Date:  1988-07       Impact factor: 7.450

Review 8.  A tumor profile in Down syndrome.

Authors:  D Satgé; D Sommelet; A Geneix; M Nishi; P Malet; M Vekemans
Journal:  Am J Med Genet       Date:  1998-07-07

9.  [Risk for Down syndrome based on maternal ages grouped in intervals of 2 and 5 years in the Mexican population].

Authors:  O Mutchinick; R Lisker; V Babinsky
Journal:  Bol Med Hosp Infant Mex       Date:  1991-08
  9 in total

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