Literature DB >> 19014926

Epidemiological association between fasting plasma glucose and shortened APTT.

Giuseppe Lippi1, Massimo Franchini, Giovanni Targher, Martina Montagnana, Gian Luca Salvagno, Gian Cesare Guidi, Emmanuel J Favaloro.   

Abstract

OBJECTIVES: To investigate the relationship between fasting plasma glucose (FPG) and shortened activated partial thromboplastin time (APTT), an independent risk factor for thrombosis. DESIGN AND METHODS: We analyzed outpatients' results of coagulation tests and FPG.
RESULTS: When compared with euglycemic subjects, those with impaired fasting glucose and diabetes displayed significantly shortened APTTs.
CONCLUSIONS: This previously unreported association deserves scrutiny, because APTT is relatively inexpensive and it might identify diabetic patients at major risk of thrombosis.

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Year:  2008        PMID: 19014926     DOI: 10.1016/j.clinbiochem.2008.10.012

Source DB:  PubMed          Journal:  Clin Biochem        ISSN: 0009-9120            Impact factor:   3.281


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