| Literature DB >> 19014886 |
Yonghui Wang1, Jakob Busch-Petersen, Feng Wang, Terence J Kiesow, Todd L Graybill, Jian Jin, Zheng Yang, James J Foley, Gerald E Hunsberger, Dulcie B Schmidt, Henry M Sarau, Elizabeth A Capper-Spudich, Zining Wu, Laura S Fisher, Michael S McQueney, Ralph A Rivero, Katherine L Widdowson.
Abstract
A series of N-arylpiperazine camphor sulfonamides was discovered as novel CXCR3 antagonists. The synthesis, structure-activity relationships, and optimization of the initial hit that resulted in the identification of potent and selective CXCR3 antagonists are described.Entities:
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Year: 2008 PMID： 19014886 DOI： 10.1016/j.bmcl.2008.11.008
Source DB: PubMed Journal: Bioorg Med Chem Lett ISSN： 0960-894X Impact factor: 2.823