| Literature DB >> 19014823 |
Aaron Hanukoglu1, Batya Curiel, Drora Berkowitz, Arieh Levine, Joseph Sack, Mordehai Lorberboym.
Abstract
Two siblings born to a mother with Wilson's disease, who was taking D-penicillamine, developed transient goitrous hypothyroidism. A prospective evaluation of 5 patients with Wilson's disease taking and not taking D-penicillamine for as long as 9.5 years showed subclinical hypothyroidism. D-penicillamine probably inhibited thyroperoxidase activity in utero in healthy infants and during childhood in patients with Wilson's disease.Entities:
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Year: 2008 PMID: 19014823 DOI: 10.1016/j.jpeds.2008.06.015
Source DB: PubMed Journal: J Pediatr ISSN: 0022-3476 Impact factor: 4.406