Upper limb lymphedema 27 (ULL27): Dutch translation and validation of an illness-specific health-related quality of life questionnaire for patients with upper limb lymphedema.

The health-related quality of life questionnaire for lymphedema of the upper limb (ULL27) was translated into Dutch according to international guidelines and validated. Eighty-four patients with lymphedema that occurred after axillary surgery for breast cancer and subsequent radiotherapy, chemotherapy, or hormonal therapy, completed the translated version of the ULL27 and the RAND36. Severity of upper limb edema was measured by specialized physiotherapists. The internal consistency of the domains of the questionnaire was good as were the convergent validity and discriminant ability. Upper limb volume and the domains of the ULL27 were not correlated. The Dutch translation of the ULL27 questionnaire has good internal consistency and validity but further research is needed to determine its responsiveness.