Literature DB >> 1901359

Sarcocystis neurona n. sp. (Protozoa: Apicomplexa), the etiologic agent of equine protozoal myeloencephalitis.

J P Dubey1, S W Davis, C A Speer, D D Bowman, A de Lahunta, D E Granstrom, M J Topper, A N Hamir, J F Cummings, M M Suter.   

Abstract

Sarcocystis neuronan n. sp. is proposed for the apicomplexan taxon associated with myeloencephalitis in horses. Only asexual stages of this parasite presently are known, and they are found within neuronal cells and leukocytes of the brain and spinal cord. The parasite is located in the host cell cytoplasm, does not have a parasitophorous vacuole, and divides by endopolygeny. Schizonts are 5-35 microns x 5-20 microns and contain 4-40 merozoites arranged in a rosette around a prominent residual body. Merozoites are approximately 4 x 1 micron, have a central nucleus, and lack rhoptries. Schizonts and merozoites react with Sarcocystis cruzi antiserum but not with Caryospora bigenetica. Toxoplasma gondii, Hammondia hammondi, or Neospora caninum antisera in an immunohistochemical test.

Entities:  

Mesh:

Year:  1991        PMID: 1901359

Source DB:  PubMed          Journal:  J Parasitol        ISSN: 0022-3395            Impact factor:   1.276


  21 in total

1.  A novel Sarcocystis neurona genotype XIII is associated with severe encephalitis in an unexpectedly broad range of marine mammals from the northeastern Pacific Ocean.

Authors:  Lorraine Barbosa; Christine K Johnson; Dyanna M Lambourn; Amanda K Gibson; Katherine H Haman; Jessica L Huggins; Amy R Sweeny; Natarajan Sundar; Stephen A Raverty; Michael E Grigg
Journal:  Int J Parasitol       Date:  2015-05-18       Impact factor: 3.981

2.  Evidence that surface proteins Sn14 and Sn16 of Sarcocystis neurona merozoites are involved in infection and immunity.

Authors:  F T Liang; D E Granstrom; X M Zhao; J F Timoney
Journal:  Infect Immun       Date:  1998-05       Impact factor: 3.441

3.  Enzyme-linked immunosorbent assays for detection of equine antibodies specific to Sarcocystis neurona surface antigens.

Authors:  Jessica S Hoane; Jennifer K Morrow; William J Saville; J P Dubey; David E Granstrom; Daniel K Howe
Journal:  Clin Diagn Lab Immunol       Date:  2005-09

4.  Reduced levels of nitric oxide metabolites in cerebrospinal fluid are associated with equine protozoal myeloencephalitis.

Authors:  Chinedu J Njoku; William J A Saville; Stephen M Reed; Michael J Oglesbee; Päivi J Rajala-Schultz; Roger W Stich
Journal:  Clin Diagn Lab Immunol       Date:  2002-05

Review 5.  An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM).

Authors:  J P Dubey; D K Howe; M Furr; W J Saville; A E Marsh; S M Reed; M E Grigg
Journal:  Vet Parasitol       Date:  2015-02-07       Impact factor: 2.738

6.  Molecular characterization of Sarcocystis neurona strains from opossums (Didelphis virginiana) and intermediate hosts from Central California.

Authors:  Daniel Rejmanek; Melissa A Miller; Michael E Grigg; Paul R Crosbie; Patricia A Conrad
Journal:  Vet Parasitol       Date:  2010-02-11       Impact factor: 2.738

7.  Serum antibodies from a subset of horses positive for Babesia caballi by competitive enzyme-linked immunosorbent assay demonstrate a protein recognition pattern that is not consistent with infection.

Authors:  Peter O Awinda; Robert H Mealey; Laura B A Williams; Patricia A Conrad; Andrea E Packham; Kathryn E Reif; Juanita F Grause; Angela M Pelzel-McCluskey; Chungwon Chung; Reginaldo G Bastos; Lowell S Kappmeyer; Daniel K Howe; SallyAnne L Ness; Donald P Knowles; Massaro W Ueti
Journal:  Clin Vaccine Immunol       Date:  2013-09-18

8.  Effects of temperature and host cell type on the in vitro growth and development of Sarcocystis falcatula.

Authors:  Hany M Elsheikha; Mahdi A Saeed; Scott D Fitzgerald; Alice J Murphy; Linda S Mansfield
Journal:  Parasitol Res       Date:  2003-07-08       Impact factor: 2.289

9.  Prevalence of Sarcocystis species sporocysts in Northern Virginia opossums (Didelphis virginiana).

Authors:  Hany M Elsheikha; Alice J Murphy; Linda S Mansfield
Journal:  Parasitol Res       Date:  2004-06-17       Impact factor: 2.289

10.  Determination of the activity of sulfadiazine against Besnoitia darlingi tachyzoites in cultured cells.

Authors:  Hany M Elsheikha; Linda S Mansfield
Journal:  Parasitol Res       Date:  2004-06-17       Impact factor: 2.289

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