Literature DB >> 19010386

Dietary activators of Sirt1.

Joanne S Allard1, Evelyn Perez, Sige Zou, Rafael de Cabo.   

Abstract

Calorie restriction (CR) is a non-genetic manipulation that reliably results in extended lifespan of several species ranging from yeast to dogs. The lifespan extension effect of CR has been strongly associated with an increased level and activation of the silent information regulator 2 (Sir2) histone deacetylase and its mammalian ortholog Sirt1. This association led to the search for potential Sirt1-activating, life-extending molecules. This review briefly outlines the experimental findings on resveratrol and other dietary activators of Sirt1.

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Year:  2008        PMID： 19010386      PMCID： PMC2727669          DOI： 10.1016/j.mce.2008.10.018

Source DB:  PubMed          Journal:  Mol Cell Endocrinol        ISSN： 0303-7207            Impact factor:   4.102


  94 in total

Review 1.  Mechanisms of life span determination in Caenorhabditis elegans.

Authors:  J R Vanfleteren; B P Braeckman
Journal:  Neurobiol Aging       Date:  1999 Sep-Oct       Impact factor: 4.673

2.  Life span is prolonged in food-restricted autoimmune-prone (NZB x NZW)F(1) mice fed a diet enriched with (n-3) fatty acids.

Authors:  C A Jolly; A Muthukumar; C P Avula; D Troyer; G Fernandes
Journal:  J Nutr       Date:  2001-10       Impact factor: 4.798

3.  Resveratrol inhibits insulin responses in a SirT1-independent pathway.

Authors:  Jiandi Zhang
Journal:  Biochem J       Date:  2006-08-01       Impact factor: 3.857

4.  Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans.

Authors:  H A Tissenbaum; L Guarente
Journal:  Nature       Date:  2001-03-08       Impact factor: 49.962

5.  Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins.

Authors:  R A Frye
Journal:  Biochem Biophys Res Commun       Date:  2000-07-05       Impact factor: 3.575

6.  A cytosolic NAD-dependent deacetylase, Hst2p, can modulate nucleolar and telomeric silencing in yeast.

Authors:  S Perrod; M M Cockell; T Laroche; H Renauld; A L Ducrest; C Bonnard; S M Gasser
Journal:  EMBO J       Date:  2001-01-15       Impact factor: 11.598

7.  Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae.

Authors:  S J Lin; P A Defossez; L Guarente
Journal:  Science       Date:  2000-09-22       Impact factor: 47.728

8.  Negative control of p53 by Sir2alpha promotes cell survival under stress.

Authors:  J Luo; A Y Nikolaev; S Imai; D Chen; F Su; A Shiloh; L Guarente; W Gu
Journal:  Cell       Date:  2001-10-19       Impact factor: 41.582

9.  hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

Authors:  H Vaziri; S K Dessain; E Ng Eaton; S I Imai; R A Frye; T K Pandita; L Guarente; R A Weinberg
Journal:  Cell       Date:  2001-10-19       Impact factor: 41.582

10.  Resveratrol inhibits intestinal tumorigenesis and modulates host-defense-related gene expression in an animal model of human familial adenomatous polyposis.

Authors:  Y Schneider; B Duranton; F Gossé; R Schleiffer; N Seiler; F Raul
Journal:  Nutr Cancer       Date:  2001       Impact factor: 2.900
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  22 in total

Review 1.  Xenohormesis: health benefits from an eon of plant stress response evolution.

Authors:  Philip L Hooper; Paul L Hooper; Michael Tytell; Lászlo Vígh
Journal:  Cell Stress Chaperones       Date:  2010-06-04       Impact factor: 3.667

2.  Resveratrol Improves Survival and Prolongs Life Following Hemorrhagic Shock.

Authors:  Ahmar Ayub; Ninu Poulose; Raghavan Raju
Journal:  Mol Med       Date:  2015-04-13       Impact factor: 6.354

3.  Closer association of mitochondria with lipid droplets in hepatocytes and activation of Kupffer cells in resveratrol-treated senescence-accelerated mice.

Authors:  Motoko Shiozaki; Naoya Hayakawa; Masahiro Shibata; Masato Koike; Yasuo Uchiyama; Takahiro Gotow
Journal:  Histochem Cell Biol       Date:  2011-08-05       Impact factor: 4.304

Review 4.  Cancer chemoprevention by dietary polyphenols: promising role for epigenetics.

Authors:  Alexander Link; Francesc Balaguer; Ajay Goel
Journal:  Biochem Pharmacol       Date:  2010-06-26       Impact factor: 5.858

Review 5.  Mechanistic understanding of β-cryptoxanthin and lycopene in cancer prevention in animal models.

Authors:  Ji Ye Lim; Xiang-Dong Wang
Journal:  Biochim Biophys Acta Mol Cell Biol Lipids       Date:  2020-02-05       Impact factor: 4.698

6.  The effect of resveratrol on lifespan depends on both gender and dietary nutrient composition in Drosophila melanogaster.

Authors:  Chunxu Wang; Charles T Wheeler; Thomas Alberico; Xiaoping Sun; Jeanne Seeberger; Mara Laslo; Edward Spangler; Bradley Kern; Rafael de Cabo; Sige Zou
Journal:  Age (Dordr)       Date:  2011-11-16

7.  Prolongevity effects of a botanical with oregano and cranberry extracts in Mexican fruit flies: examining interactions of diet restriction and age.

Authors:  Sige Zou; James R Carey; Pablo Liedo; Donald K Ingram; Binbing Yu
Journal:  Age (Dordr)       Date:  2011-04-01

Review 8.  Macronutrients and caloric intake in health and longevity.

Authors:  Samantha M Solon-Biet; Sarah J Mitchell; Rafael de Cabo; David Raubenheimer; David G Le Couteur; Stephen J Simpson
Journal:  J Endocrinol       Date:  2015-05-28       Impact factor: 4.286

9.  Nectarine promotes longevity in Drosophila melanogaster.

Authors:  Olga Boyd; Peter Weng; Xiaoping Sun; Thomas Alberico; Mara Laslo; David M Obenland; Bradley Kern; Sige Zou
Journal:  Free Radic Biol Med       Date:  2011-03-13       Impact factor: 7.376

10.  Prolongevity effects of an oregano and cranberry extract are diet dependent in the Mexican fruit fly (Anastrepha ludens).

Authors:  Sige Zou; James R Carey; Pablo Liedo; Donald K Ingram; Binbing Yu; Reza Ghaedian
Journal:  J Gerontol A Biol Sci Med Sci       Date:  2009-11-11       Impact factor: 6.053
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