Literature DB >> 19010328

Outpatient management of nonvariceal upper gastrointestinal hemorrhage: unexpected mortality in Medicare beneficiaries.

Gregory S Cooper1, Tzyung Doug Kou, Richard C K Wong.   

Abstract

BACKGROUND & AIMS: Outpatient management of selected patients with nonvariceal upper gastrointestinal hemorrhage (UGIH) has been proposed as a mechanism to decrease resource utilization and expenditures. However, the true prevalence and outcomes of this practice have not been well evaluated in population-based studies.
METHODS: We identified a cohort of 9123 episodes of UGIH in 2004 Medicare claims data, including 3506 (38.4%) managed as outpatients. Clinical characteristics, treatment, and outcomes were compared between inpatient and outpatient groups. In order to adjust for potential selection bias in outpatient treatment, propensity score analysis was used to divide patients into quartiles of likelihood for inpatient treatment.
RESULTS: Inpatients tended to be older, with higher comorbidity scores, and were more likely to have a bleeding ulcer or tear. Inpatients were also more likely to undergo endoscopy, including early endoscopy and therapeutics, and require surgery. The overall 30-day mortality rate was 8.0% in the inpatient group and 6.3% in the outpatient group (P< .001), and in the quartile of patients most likely to be managed as inpatients, the 30-day mortality rate was higher in outpatients than in inpatients.
CONCLUSIONS: The prevalence of outpatient management of UGIH in the Medicare population was almost 40%, and although patients were likely selected for outpatient management based on clinical criteria, the overall mortality rate in outpatients was considerable. Any potential financial benefit should be balanced against significant mortality rates, at least some of which could possibly be avoided with hospitalization. More optimal selection of candidates for outpatient therapy is likely needed.

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Year:  2008        PMID: 19010328     DOI: 10.1053/j.gastro.2008.09.030

Source DB:  PubMed          Journal:  Gastroenterology        ISSN: 0016-5085            Impact factor:   22.682


  10 in total

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Authors:  Ju-Yeh Yang; Tsung-Chun Lee; Maria E Montez-Rath; Jane Paik; Glenn M Chertow; Manisha Desai; Wolfgang C Winkelmayer
Journal:  J Am Soc Nephrol       Date:  2012-01-19       Impact factor: 10.121

2.  Mortality following blood transfusion for non-variceal upper gastrointestinal bleeding.

Authors:  Ali S Taha; Caroline McCloskey; Theresa Craigen; Wilson J Angerson; Amir A Shah; Christopher G Morran
Journal:  Frontline Gastroenterol       Date:  2011-07-16

Review 3.  Optimal management of peptic ulcer disease in the elderly.

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Journal:  Drugs Aging       Date:  2010-07-01       Impact factor: 3.923

Review 4.  Why do mortality rates for nonvariceal upper gastrointestinal bleeding differ around the world? A systematic review of cohort studies.

Authors:  Vipul Jairath; Myriam Martel; Richard F A Logan; Alan N Barkun
Journal:  Can J Gastroenterol       Date:  2012-08       Impact factor: 3.522

5.  Long-term risk of upper gastrointestinal hemorrhage after advanced AKI.

Authors:  Pei-Chen Wu; Chih-Jen Wu; Cheng-Jui Lin; Vin-Cent Wu
Journal:  Clin J Am Soc Nephrol       Date:  2014-12-19       Impact factor: 8.237

Review 6.  Diagnosis and management of nonvariceal upper gastrointestinal bleeding.

Authors:  Marc Bardou; Dalila Benhaberou-Brun; Isabelle Le Ray; Alan N Barkun
Journal:  Nat Rev Gastroenterol Hepatol       Date:  2012-01-10       Impact factor: 46.802

7.  The Comprehensive Geriatric Assessment and the multidimensional approach. A new look at the older patient with gastroenterological disorders.

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Journal:  Best Pract Res Clin Gastroenterol       Date:  2009       Impact factor: 3.043

8.  Risk factors of short-term mortality after acute nonvariceal upper gastrointestinal bleeding in patients on dialysis: a population-based study.

Authors:  Ju-Yeh Yang; Tsung-Chun Lee; Maria E Montez-Rath; Glenn M Chertow; Wolfgang C Winkelmayer
Journal:  BMC Nephrol       Date:  2013-04-26       Impact factor: 2.388

9.  Reductions in 28-day mortality following hospital admission for upper gastrointestinal hemorrhage.

Authors:  Colin Crooks; Tim Card; Joe West
Journal:  Gastroenterology       Date:  2011-03-27       Impact factor: 22.682

10.  Gastrointestinal Hemorrhage in Acute Kidney Injury Patients on Hemodialysis.

Authors:  Shantanu Solanki; Khwaja F Haq; Muhammad Ali Khan; Raja Chandra Chakinala; Siddharth Mehta; Khwaja S Haq; Uvesh Mansuri; Zubair Khan; Darshan Gandhi; Jagmeet Singh; Savneek S Chugh
Journal:  Cureus       Date:  2019-09-13
  10 in total

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