OBJECTIVE: The interrupter technique is used for determining interrupter resistance (Rint) during quiet breathing. This noninvasive method requires minimal cooperation and can therefore be useful in evaluating airway obstruction in uncooperative children. To date, no reference values have been determined for Rint in a Brazilian population. The objective of this study was to define a prediction equation for airway resistance using the interrupter technique for healthy children aged 3-13 years. METHODS: This was a prospective, cross-sectional study involving preschool and school children in Porto Alegre, Brazil, in whom Rint was measured during peak expiratory flow. RESULTS: One-hundred and ninety-three children were evaluated. Univariate analysis using linear regression showed that height, weight and age correlated significantly and independently with Rint. Multiple regression with height, weight, age and gender as variables resulted in a model in which only height and weight were significant, independent predictors of Rint. Collinearity was identified among height, weight and age. CONCLUSIONS: Reference values and an equation for calculating Rint in healthy children were obtained and are adjusted for height.
OBJECTIVE: The interrupter technique is used for determining interrupter resistance (Rint) during quiet breathing. This noninvasive method requires minimal cooperation and can therefore be useful in evaluating airway obstruction in uncooperative children. To date, no reference values have been determined for Rint in a Brazilian population. The objective of this study was to define a prediction equation for airway resistance using the interrupter technique for healthy children aged 3-13 years. METHODS: This was a prospective, cross-sectional study involving preschool and school children in Porto Alegre, Brazil, in whom Rint was measured during peak expiratory flow. RESULTS: One-hundred and ninety-three children were evaluated. Univariate analysis using linear regression showed that height, weight and age correlated significantly and independently with Rint. Multiple regression with height, weight, age and gender as variables resulted in a model in which only height and weight were significant, independent predictors of Rint. Collinearity was identified among height, weight and age. CONCLUSIONS: Reference values and an equation for calculating Rint in healthy children were obtained and are adjusted for height.
Authors: Malin Barman; Fiona Murray; Angelina I Bernardi; Karin Broberg; Sven Bölte; Bill Hesselmar; Bo Jacobsson; Karin Jonsson; Maria Kippler; Hardis Rabe; Alastair B Ross; Fei Sjöberg; Nicklas Strömberg; Marie Vahter; Agnes E Wold; Ann-Sofie Sandberg; Anna Sandin Journal: BMJ Open Date: 2018-10-21 Impact factor: 2.692