Literature DB >> 19008882

Bcl-2 turns deadly.

Bing Qi, J Marie Hardwick.   

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Year:  2008        PMID： 19008882      PMCID： PMC2630477          DOI： 10.1038/nchembio1208-722

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN： 1552-4450            Impact factor:   15.040


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  10 in total

1.  Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma.

Authors:  Frederic Luciano; Maryla Krajewska; Paulina Ortiz-Rubio; Stan Krajewski; Dayong Zhai; Benjamin Faustin; Jean-Marie Bruey; Beatrice Bailly-Maitre; Alan Lichtenstein; Siva Kumar Kolluri; Arnold C Satterthwait; Xiao-Kun Zhang; John C Reed
Journal:  Blood       Date:  2007-01-16       Impact factor: 22.113

2.  Modulation of cell death by Bcl-XL through caspase interaction.

Authors:  R J Clem; E H Cheng; C L Karp; D G Kirsch; K Ueno; A Takahashi; M B Kastan; D E Griffin; W C Earnshaw; M A Veliuona; J M Hardwick
Journal:  Proc Natl Acad Sci U S A       Date:  1998-01-20       Impact factor: 11.205

3.  An inhibitor of Bcl-2 family proteins induces regression of solid tumours.

Authors:  Tilman Oltersdorf; Steven W Elmore; Alexander R Shoemaker; Robert C Armstrong; David J Augeri; Barbara A Belli; Milan Bruncko; Thomas L Deckwerth; Jurgen Dinges; Philip J Hajduk; Mary K Joseph; Shinichi Kitada; Stanley J Korsmeyer; Aaron R Kunzer; Anthony Letai; Chi Li; Michael J Mitten; David G Nettesheim; ShiChung Ng; Paul M Nimmer; Jacqueline M O'Connor; Anatol Oleksijew; Andrew M Petros; John C Reed; Wang Shen; Stephen K Tahir; Craig B Thompson; Kevin J Tomaselli; Baole Wang; Michael D Wendt; Haichao Zhang; Stephen W Fesik; Saul H Rosenberg
Journal:  Nature       Date:  2005-05-15       Impact factor: 49.962

4.  Conversion of Bcl-2 to a Bax-like death effector by caspases.

Authors:  E H Cheng; D G Kirsch; R J Clem; R Ravi; M B Kastan; A Bedi; K Ueno; J M Hardwick
Journal:  Science       Date:  1997-12-12       Impact factor: 47.728

5.  Bcl-xL inhibitor ABT-737 reveals a dual role for Bcl-xL in synaptic transmission.

Authors:  John A Hickman; J Marie Hardwick; Leonard K Kaczmarek; Elizabeth A Jonas
Journal:  J Neurophysiol       Date:  2007-12-26       Impact factor: 2.714

6.  A TR3/Nur77 peptide-based high-throughput fluorescence polarization screen for small molecule Bcl-B inhibitors.

Authors:  Kenneth W Yip; Paulo H C Godoi; Dayong Zhai; Xochella Garcia; Jason F Cellitti; Michael Cuddy; Motti Gerlic; Ya Chen; Arnold Satterthwait; Stefan Vasile; Eduard Sergienko; John C Reed
Journal:  J Biomol Screen       Date:  2008-07-14

7.  Bcl-B expression in human epithelial and nonepithelial malignancies.

Authors:  Maryla Krajewska; Shinichi Kitada; Jane N Winter; Daina Variakojis; Alan Lichtenstein; Dayong Zhai; Michael Cuddy; Xianshu Huang; Frederic Luciano; Cheryl H Baker; Hoguen Kim; Eunah Shin; Susan Kennedy; Allen H Olson; Andrzej Badzio; Jacek Jassem; Ivo Meinhold-Heerlein; Michael J Duffy; Aaron D Schimmer; Ming Tsao; Ewan Brown; Anne Sawyers; Michael Andreeff; Dan Mercola; Stan Krajewski; John C Reed
Journal:  Clin Cancer Res       Date:  2008-05-15       Impact factor: 12.531

8.  A short Nur77-derived peptide converts Bcl-2 from a protector to a killer.

Authors:  Siva Kumar Kolluri; Xiuwen Zhu; Xin Zhou; Bingzhen Lin; Ya Chen; Kai Sun; Xuefei Tian; James Town; Xihua Cao; Feng Lin; Dayong Zhai; Shinichi Kitada; Frederick Luciano; Edmond O'Donnell; Yu Cao; Feng He; Jialing Lin; John C Reed; Arnold C Satterthwait; Xiao-kun Zhang
Journal:  Cancer Cell       Date:  2008-10-07       Impact factor: 31.743

9.  BAX activation is initiated at a novel interaction site.

Authors:  Evripidis Gavathiotis; Motoshi Suzuki; Marguerite L Davis; Kenneth Pitter; Gregory H Bird; Samuel G Katz; Ho-Chou Tu; Hyungjin Kim; Emily H-Y Cheng; Nico Tjandra; Loren D Walensky
Journal:  Nature       Date:  2008-10-23       Impact factor: 49.962

10.  During negative selection, Nur77 family proteins translocate to mitochondria where they associate with Bcl-2 and expose its proapoptotic BH3 domain.

Authors:  Jennifer Thompson; Astar Winoto
Journal:  J Exp Med       Date:  2008-04-28       Impact factor: 14.307
  10 in total

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