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Literature DB >> 19008217

SUMOylation and De-SUMOylation: wrestling with life's processes.

Abstract

The small ubiquitin-like modifier (SUMO) is a ubiquitin-like protein that covalently modifies a large number of cellular proteins. SUMO modification has emerged as an important regulatory mechanism for protein function and localization. SUMOylation is a dynamic process that is mediated by activating (E1), conjugating (E2), and ligating (E3) enzymes and readily reversed by a family of ubiquitin-like protein-specific proteases (Ulp) in yeast and sentrin/SUMO-specific proteases (SENP) in human. This review will focus on the de-SUMOylating enzymes with special attention to their biological function.

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Year: 2008 PMID： 19008217 PMCID： PMC2659178 DOI： 10.1074/jbc.R800050200

Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157

50 in total

1. Differential regulation of sentrinized proteins by a novel sentrin-specific protease.

Authors: L Gong; S Millas; G G Maul; E T Yeh
Journal: J Biol Chem Date: 2000-02-04 Impact factor: 5.157

2. A new SUMO-1-specific protease, SUSP1, that is highly expressed in reproductive organs.

Authors: K I Kim; S H Baek; Y J Jeon; S Nishimori; T Suzuki; S Uchida; N Shimbara; H Saitoh; K Tanaka; C H Chung
Journal: J Biol Chem Date: 2000-05-12 Impact factor: 5.157

Review 3. Ubiquitin-like proteins: new wines in new bottles.

Authors: E T Yeh; L Gong; T Kamitani
Journal: Gene Date: 2000-05-02 Impact factor: 3.688

4. Ulp1-SUMO crystal structure and genetic analysis reveal conserved interactions and a regulatory element essential for cell growth in yeast.

Authors: E Mossessova; C D Lima
Journal: Mol Cell Date: 2000-05 Impact factor: 17.970

5. Basic Medical Research Award. The ubiquitin system.

Authors: A Hershko; A Ciechanover; A Varshavsky
Journal: Nat Med Date: 2000-10 Impact factor: 53.440

6. A novel mammalian Smt3-specific isopeptidase 1 (SMT3IP1) localized in the nucleolus at interphase.

Authors: T Nishida; H Tanaka; H Yasuda
Journal: Eur J Biochem Date: 2000-11

7. An E3-like factor that promotes SUMO conjugation to the yeast septins.

Authors: E S Johnson; A A Gupta
Journal: Cell Date: 2001-09-21 Impact factor: 41.582

8. Covalent modification of the androgen receptor by small ubiquitin-like modifier 1 (SUMO-1).

Authors: H Poukka; U Karvonen; O A Janne; J J Palvimo
Journal: Proc Natl Acad Sci U S A Date: 2000-12-19 Impact factor: 11.205

9. Involvement of PIAS1 in the sumoylation of tumor suppressor p53.

Authors: T Kahyo; T Nishida; H Yasuda
Journal: Mol Cell Date: 2001-09 Impact factor: 17.970

10. The Ulp1 SUMO isopeptidase: distinct domains required for viability, nuclear envelope localization, and substrate specificity.

Authors: Shyr-Jiann Li; Mark Hochstrasser
Journal: J Cell Biol Date: 2003-03-24 Impact factor: 10.539

214 in total

1. An in vitro Förster resonance energy transfer-based high-throughput screening assay for inhibitors of protein-protein interactions in SUMOylation pathway.

Authors: Yang Song; Jiayu Liao
Journal: Assay Drug Dev Technol Date: 2011-12-22 Impact factor: 1.738

Review 2. Trojan horse strategies used by pathogens to influence the small ubiquitin-like modifier (SUMO) system of host eukaryotic cells.

Authors: Miklós Békés; Marcin Drag
Journal: J Innate Immun Date: 2012-01-03 Impact factor: 7.349

3. Expanding NFκB and SUMO ties.

Authors: Moon-Hee Lee; Shigeki Miyamoto
Journal: Cell Cycle Date: 2011-12-01 Impact factor: 4.534

4. Small ubiquitin-like modifier (SUMO) modification mediates function of the inhibitory domains of developmental regulators FOXC1 and FOXC2.

Authors: Theodora E Danciu; Sergey Chupreta; Osvaldo Cruz; Jennifer E Fox; Malcolm Whitman; Jorge A Iñiguez-Lluhí
Journal: J Biol Chem Date: 2012-04-05 Impact factor: 5.157

5. Cardiovascular biology: heart fails without pump partner.

Authors: Sudha K Shenoy; Howard A Rockman
Journal: Nature Date: 2011-09-28 Impact factor: 49.962

6. PIASy-mediated Tip60 sumoylation regulates p53-induced autophagy.

Authors: Samisubbu R Naidu; Alexander J Lakhter; Elliot J Androphy
Journal: Cell Cycle Date: 2012-07-15 Impact factor: 4.534

7. De-SUMOylation enzyme of sentrin/SUMO-specific protease 2 regulates disturbed flow-induced SUMOylation of ERK5 and p53 that leads to endothelial dysfunction and atherosclerosis.

Authors: Kyung-Sun Heo; Eugene Chang; Nhat-Tu Le; Hannah Cushman; Edward T H Yeh; Keigi Fujiwara; Jun-ichi Abe
Journal: Circ Res Date: 2013-02-04 Impact factor: 17.367

8. Isocitrate-to-SENP1 signaling amplifies insulin secretion and rescues dysfunctional β cells.

Authors: Mourad Ferdaoussi; Xiaoqing Dai; Mette V Jensen; Runsheng Wang; Brett S Peterson; Chao Huang; Olga Ilkayeva; Nancy Smith; Nathanael Miller; Catherine Hajmrle; Aliya F Spigelman; Robert C Wright; Gregory Plummer; Kunimasa Suzuki; James P Mackay; Martijn van de Bunt; Anna L Gloyn; Terence E Ryan; Lisa D Norquay; M Julia Brosnan; Jeff K Trimmer; Timothy P Rolph; Richard G Kibbey; Jocelyn E Manning Fox; William F Colmers; Orian S Shirihai; P Darrell Neufer; Edward T H Yeh; Christopher B Newgard; Patrick E MacDonald
Journal: J Clin Invest Date: 2015-09-21 Impact factor: 14.808

9. SUMOylation of hnRNP-K is required for p53-mediated cell-cycle arrest in response to DNA damage.

Authors: Seong Won Lee; Moon Hee Lee; Jong Ho Park; Sung Hwan Kang; Hee Min Yoo; Seung Hyun Ka; Young Mi Oh; Young Joo Jeon; Chin Ha Chung
Journal: EMBO J Date: 2012-10-23 Impact factor: 11.598

10. The SUMO-Specific Protease Senp2 Regulates SUMOylation, Expression and Function of Human Organic Anion Transporter 3.

Authors: Haoxun Wang; Guofeng You
Journal: Biochim Biophys Acta Biomembr Date: 2019-05-01 Impact factor: 3.747