Literature DB >> 19007963

The human papillomavirus E7 oncoprotein.

Margaret E McLaughlin-Drubin1, Karl Münger.   

Abstract

The human papillomavirus (HPV) E7 oncoprotein shares functional similarities with such proteins as adenovirus E1A and SV40 large tumor antigen. As one of only two viral proteins always expressed in HPV-associated cancers, E7 plays a central role in both the viral life cycle and carcinogenic transformation. In the HPV viral life cycle, E7 disrupts the intimate association between cellular differentiation and proliferation in normal epithelium, allowing for viral replication in cells that would no longer be in the dividing population. This function is directly reflected in the transforming activities of E7, including tumor initiation and induction of genomic instability.

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Year:  2008        PMID： 19007963      PMCID： PMC2661820          DOI： 10.1016/j.virol.2008.10.006

Source DB:  PubMed          Journal:  Virology        ISSN： 0042-6822            Impact factor:   3.616


  209 in total

1.  Destabilization of the retinoblastoma tumor suppressor by human papillomavirus type 16 E7 is not sufficient to overcome cell cycle arrest in human keratinocytes.

Authors:  A M Helt; D A Galloway
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

Review 2.  Anoikis mechanisms.

Authors:  S M Frisch; R A Screaton
Journal:  Curr Opin Cell Biol       Date:  2001-10       Impact factor: 8.382

3.  A complex with chromatin modifiers that occupies E2F- and Myc-responsive genes in G0 cells.

Authors:  Hidesato Ogawa; Kei-Ichiro Ishiguro; Stefan Gaubatz; David M Livingston; Yoshihiro Nakatani
Journal:  Science       Date:  2002-05-10       Impact factor: 47.728

4.  Human papillomavirus type 16 E7 binds to E2F1 and activates E2F1-driven transcription in a retinoblastoma protein-independent manner.

Authors:  Sun Gwan Hwang; Daeyoup Lee; Jiyun Kim; Taegun Seo; Joonho Choe
Journal:  J Biol Chem       Date:  2001-11-16       Impact factor: 5.157

5.  The cytokines tumor necrosis factor-alpha (TNF-alpha ) and TNF-related apoptosis-inducing ligand differentially modulate proliferation and apoptotic pathways in human keratinocytes expressing the human papillomavirus-16 E7 oncoprotein.

Authors:  J R Basile; V Zacny; K Münger
Journal:  J Biol Chem       Date:  2001-04-16       Impact factor: 5.157

6.  Stabilization and functional impairment of the tumor suppressor p53 by the human papillomavirus type 16 E7 oncoprotein.

Authors:  Alexandra Eichten; Matthew Westfall; Jennifer A Pietenpol; Karl Münger
Journal:  Virology       Date:  2002-03-30       Impact factor: 3.616

7.  Centrosome abnormalities and genomic instability by episomal expression of human papillomavirus type 16 in raft cultures of human keratinocytes.

Authors:  S Duensing; A Duensing; E R Flores; A Do; P F Lambert; K Münger
Journal:  J Virol       Date:  2001-08       Impact factor: 5.103

8.  Induction of the bovine papillomavirus origin "onion skin"-type DNA replication at high E1 protein concentrations in vivo.

Authors:  Andres Männik; Kertu Rünkorg; Nele Jaanson; Mart Ustav; Ene Ustav
Journal:  J Virol       Date:  2002-06       Impact factor: 5.103

9.  BIG: a calossin-like protein required for polar auxin transport in Arabidopsis.

Authors:  P Gil; E Dewey; J Friml; Y Zhao; K C Snowden; J Putterill; K Palme; M Estelle; J Chory
Journal:  Genes Dev       Date:  2001-08-01       Impact factor: 11.361

Review 10.  Papillomaviruses and cancer: from basic studies to clinical application.

Authors:  Harald zur Hausen
Journal:  Nat Rev Cancer       Date:  2002-05       Impact factor: 60.716
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  166 in total

Review 1.  Estrogen and ERalpha: culprits in cervical cancer?

Authors:  Sang-Hyuk Chung; Silvia Franceschi; Paul F Lambert
Journal:  Trends Endocrinol Metab       Date:  2010-04-22       Impact factor: 12.015

2.  The E6 oncoprotein from HPV16 enhances the canonical Wnt/β-catenin pathway in skin epidermis in vivo.

Authors:  José Bonilla-Delgado; Gülay Bulut; Xuefeng Liu; Enoc M Cortés-Malagón; Richard Schlegel; Catalina Flores-Maldonado; Rubén G Contreras; Sang-Hyuk Chung; Paul F Lambert; Aykut Uren; Patricio Gariglio
Journal:  Mol Cancer Res       Date:  2011-12-07       Impact factor: 5.852

3.  Detection of human papillomavirus type 18 E7 oncoprotein in cervical smears: a feasibility study.

Authors:  Daniela Ehehalt; Barbara Lener; Haymo Pircher; Kerstin Dreier; Heiko Pfister; Andreas M Kaufmann; Sergio Frangini; Sigrun Ressler; Elisabeth Müller-Holzner; Markus Schmitt; Daniela Höfler; Ursula Rostek; Andreas Kaiser; Andreas Widschwendter; Werner Zwerschke; Pidder Jansen-Dürr
Journal:  J Clin Microbiol       Date:  2011-11-30       Impact factor: 5.948

Review 4.  Cellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk viruses.

Authors:  Aloysius J Klingelhutz; Ann Roman
Journal:  Virology       Date:  2012-01-27       Impact factor: 3.616

5.  Targeting the human papillomavirus E6 and E7 oncogenes through expression of the bovine papillomavirus type 1 E2 protein stimulates cellular motility.

Authors:  Monique A Morrison; Richard J Morreale; Shailaja Akunuru; Matthew Kofron; Yi Zheng; Susanne I Wells
Journal:  J Virol       Date:  2011-08-10       Impact factor: 5.103

Review 6.  Genomic instability and cancer: lessons learned from human papillomaviruses.

Authors:  Nina Korzeniewski; Nicole Spardy; Anette Duensing; Stefan Duensing
Journal:  Cancer Lett       Date:  2010-11-13       Impact factor: 8.679

7.  Chlamydial infection induces host cytokinesis failure at abscission.

Authors:  Heather M Brown; Andrea E Knowlton; Scott S Grieshaber
Journal:  Cell Microbiol       Date:  2012-06-19       Impact factor: 3.715

8.  Human parvovirus B19 causes cell cycle arrest of human erythroid progenitors via deregulation of the E2F family of transcription factors.

Authors:  Zhihong Wan; Ning Zhi; Susan Wong; Keyvan Keyvanfar; Delong Liu; Nalini Raghavachari; Peter J Munson; Su Su; Daniela Malide; Sachiko Kajigaya; Neal S Young
Journal:  J Clin Invest       Date:  2010-09-20       Impact factor: 14.808

9.  Gene expression profile regulated by the HPV16 E7 oncoprotein and estradiol in cervical tissue.

Authors:  Enoc M Cortés-Malagón; José Bonilla-Delgado; José Díaz-Chávez; Alfredo Hidalgo-Miranda; Sandra Romero-Cordoba; Aykut Uren; Haydar Celik; Matthew McCormick; José A Munguía-Moreno; Eloisa Ibarra-Sierra; Jaime Escobar-Herrera; Paul F Lambert; Daniel Mendoza-Villanueva; Rosa M Bermudez-Cruz; Patricio Gariglio
Journal:  Virology       Date:  2013-09-27       Impact factor: 3.616

Review 10.  Papillomavirus prophylactic vaccines: established successes, new approaches.

Authors:  M Saveria Campo; Richard B S Roden
Journal:  J Virol       Date:  2009-11-11       Impact factor: 5.103
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