Literature DB >> 19006688

A renaissance in understanding the multiple and diverse functions of granzymes?

Joseph A Trapani1, Phillip I Bird.   

Abstract

In this issue of Immunity, Metkar et al. (2008) present evidence that granzyme A plays a role in inflammatory signaling and that contrary to previous studies, it is incapable of inducing target cell death. The work challenges us to reconsider the broader biological roles of all the granzymes.

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Year:  2008        PMID: 19006688     DOI: 10.1016/j.immuni.2008.10.002

Source DB:  PubMed          Journal:  Immunity        ISSN: 1074-7613            Impact factor:   31.745


  9 in total

Review 1.  Natural killer cell cytotoxicity: how do they pull the trigger?

Authors:  Nicola J Topham; Eric W Hewitt
Journal:  Immunology       Date:  2009-09       Impact factor: 7.397

2.  Granzyme B-induced and caspase 3-dependent cleavage of gelsolin by mouse cytotoxic T cells modifies cytoskeleton dynamics.

Authors:  Praxedis Martin; Julián Pardo; Natalie Schill; Lars Jöckel; Matthias Berg; Christopher J Froelich; Reinhard Wallich; Markus M Simon
Journal:  J Biol Chem       Date:  2010-04-15       Impact factor: 5.157

3.  Cd226-/- natural killer cells fail to establish stable contacts with cancer cells and show impaired control of tumor metastasis in vivo.

Authors:  Ji Sung Kim; Bo Ram Shin; Hong Kyung Lee; Jae Hee Lee; Ki Hun Kim; Jeong Eun Choi; A Young Ji; Jin Tae Hong; Youngsoo Kim; Sang-Bae Han
Journal:  Oncoimmunology       Date:  2017-07-05       Impact factor: 8.110

4.  Mouse cytotoxic T cell-derived granzyme B activates the mitochondrial cell death pathway in a Bim-dependent fashion.

Authors:  Elena Catalán; Paula Jaime-Sánchez; Nacho Aguiló; Markus M Simon; Christopher J Froelich; Julián Pardo
Journal:  J Biol Chem       Date:  2015-01-20       Impact factor: 5.157

Review 5.  Off-the-Shelf Chimeric Antigen Receptor Immune Cells from Human Pluripotent Stem Cells.

Authors:  Handi Cao; Ryohichi Sugimura
Journal:  Cancer Treat Res       Date:  2022

6.  Granzyme A- and B-cluster deficiency delays acute lung injury in pneumovirus-infected mice.

Authors:  Reinout A Bem; Job B M van Woensel; Rene Lutter; Joseph B Domachowske; Jan Paul Medema; Helene F Rosenberg; Albert P Bos
Journal:  J Immunol       Date:  2009-12-16       Impact factor: 5.422

7.  Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis.

Authors:  Athena M Soulika; Eunyoung Lee; Erica McCauley; Laird Miers; Peter Bannerman; David Pleasure
Journal:  J Neurosci       Date:  2009-11-25       Impact factor: 6.167

8.  Japanese encephalitis virus infection induces changes of mRNA profile of mouse spleen and brain.

Authors:  Yang Yang; Jing Ye; Xiaohong Yang; Rong Jiang; Huanchun Chen; Shengbo Cao
Journal:  Virol J       Date:  2011-02-24       Impact factor: 4.099

Review 9.  Innate Lymphoid Cells (ILCs) as Mediators of Inflammation, Release of Cytokines and Lytic Molecules.

Authors:  Noha Mousaad Elemam; Suad Hannawi; Azzam A Maghazachi
Journal:  Toxins (Basel)       Date:  2017-12-10       Impact factor: 4.546

  9 in total

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