BACKGROUND: To date, many health status instruments exist, but the validity of these instruments is questionable. This is caused by the fact that health status is poorly defined. PURPOSE: To develop a validated framework that improves conceptual insight into health status and its domains. METHODS: Based on theoretical and clinical considerations, we defined the domains of health status into concrete sub-domains by formulating conceptual models. Guided by these conceptual models, for each sub-domain, existing instruments were selected. We validated the conceptual models in the data of 168 COPD patients. Using factor analysis, underlying concepts in the data were identified. RESULTS: The resulting framework included physiological functioning, complaints, functional impairment, and quality of life. These main domains were shown to be subdivided into 15 sub-domains. CONCLUSIONS: The present study shows that health status consists of conceptually distinct sub-domains. Integral assessment of health status thus entails measuring all sub-domains. Existing instruments measure only few sub-domains. Integral assessment of health status thus requires the combination of different instruments. The present framework of health status can help in composing such a battery of instruments. Patient profiles obtained by the framework are essential in individualizing treatment.
BACKGROUND: To date, many health status instruments exist, but the validity of these instruments is questionable. This is caused by the fact that health status is poorly defined. PURPOSE: To develop a validated framework that improves conceptual insight into health status and its domains. METHODS: Based on theoretical and clinical considerations, we defined the domains of health status into concrete sub-domains by formulating conceptual models. Guided by these conceptual models, for each sub-domain, existing instruments were selected. We validated the conceptual models in the data of 168 COPDpatients. Using factor analysis, underlying concepts in the data were identified. RESULTS: The resulting framework included physiological functioning, complaints, functional impairment, and quality of life. These main domains were shown to be subdivided into 15 sub-domains. CONCLUSIONS: The present study shows that health status consists of conceptually distinct sub-domains. Integral assessment of health status thus entails measuring all sub-domains. Existing instruments measure only few sub-domains. Integral assessment of health status thus requires the combination of different instruments. The present framework of health status can help in composing such a battery of instruments. Patient profiles obtained by the framework are essential in individualizing treatment.
Authors: Leonie Daudey; Jeannette B Peters; Johan Molema; P N Richard Dekhuijzen; Judith B Prins; Yvonne F Heijdra; Jan H Vercoulen Journal: Respir Res Date: 2010-07-22
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Authors: Wouter D van Dijk; Lisette van den Bemt; Saskia van den Haak-Rongen; Erik Bischoff; Chris van Weel; Johannes C C M in 't Veen; Tjard R J Schermer Journal: Respir Res Date: 2011-11-14
Authors: Tewe L Verhage; Yvonne F Heijdra; Johan Molema; Leonie Daudey; P N Richard Dekhuijzen; Jan H Vercoulen Journal: Open Respir Med J Date: 2009-02-13
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Authors: Edmée F M M van den Akker; Alex J van 't Hul; Niels H Chavannes; Gert-Jan Braunstahl; Alie van Bruggen; Maureen P M H Rutten-van Mölken; Johannes C C M In 't Veen Journal: Int J Chron Obstruct Pulmon Dis Date: 2015-11-06