INTRODUCTION: Paraneoplastic neurological disorders are rare complications of breast carcinoma. Lambert-Eaton Myasthenic Syndrome (LEMS) is most commonly associated with small cell lung cancer. However, a combination of LEMS and subacute cerebellar degeneration as paraneoplastic syndromes is extremely rare, and has never been described in association with breast cancer. CASE: We report for the first time an unusual association of LEMS and paraneoplastic subacute cerebellar degeneration with breast carcinoma. CONCLUSION: In patients with atypical LEMS, when there is no evidence of respiratory malignancy, breast cancer should be included in the differential diagnosis.
INTRODUCTION:Paraneoplastic neurological disorders are rare complications of breast carcinoma. Lambert-Eaton Myasthenic Syndrome (LEMS) is most commonly associated with small cell lung cancer. However, a combination of LEMS and subacute cerebellar degeneration as paraneoplastic syndromes is extremely rare, and has never been described in association with breast cancer. CASE: We report for the first time an unusual association of LEMS and paraneoplastic subacute cerebellar degeneration with breast carcinoma. CONCLUSION: In patients with atypical LEMS, when there is no evidence of respiratory malignancy, breast cancer should be included in the differential diagnosis.
Authors: W P Mason; F Graus; B Lang; J Honnorat; J Y Delattre; F Valldeoriola; J C Antoine; M K Rosenblum; M R Rosenfeld; J Newsom-Davis; J B Posner; J Dalmau Journal: Brain Date: 1997-08 Impact factor: 13.501
Authors: Paul W Wirtz; Bethan Lang; Francesc Graus; Arn M J M van den Maagdenberg; Albert Saiz; Pia A de Koning Gans; Albert Twijnstra; Jan J G M Verschuuren Journal: J Neuroimmunol Date: 2005-07 Impact factor: 3.478
Authors: G Gatti; S Simsek; A Kurne; S Zurrida; P Naninato; P Veronesi; A Frasson; E Millen; J Rososchansky; A Luini Journal: Breast Date: 2003-06 Impact factor: 4.380