Leila Kheirandish-Gozal1, David Gozal. 1. Division of Pediatric Sleep Medicine, Department of Pediatrics, University of Louisville, Louisville, Kentucky, USA.
Abstract
PURPOSE OF REVIEW: To review some of the inherent problems in defining the diagnosis of pediatric obstructive sleep apnea (OSA) and propose a novel approach to clinical evaluation and referral of habitually snoring children. RECENT FINDINGS: OSA has emerged in the last 30 years as a highly prevalent condition in children. However, the diagnostic uncertainties associated with the clinical presentation and physical examination, and changes in the clinical phenotype over time dictated by the escalation of obesity in children, along with the objective difficulties in accessing appropriately equipped sleep laboratories, have led to substantial underrecognition and to implementation of empirically driven treatment interventions for which scientific validity and efficacy remain undefined. SUMMARY: Current tools for the diagnosis of OSA in children are labor-intensive, and onerous, and remain unvalidated. Novel diagnostic approaches linking objective physiological, biological, or both, measures to defined outcomes of pediatric OSA need to be developed and validated to enable wider and earlier recognition of this condition.
PURPOSE OF REVIEW: To review some of the inherent problems in defining the diagnosis of pediatric obstructive sleep apnea (OSA) and propose a novel approach to clinical evaluation and referral of habitually snoring children. RECENT FINDINGS: OSA has emerged in the last 30 years as a highly prevalent condition in children. However, the diagnostic uncertainties associated with the clinical presentation and physical examination, and changes in the clinical phenotype over time dictated by the escalation of obesity in children, along with the objective difficulties in accessing appropriately equipped sleep laboratories, have led to substantial underrecognition and to implementation of empirically driven treatment interventions for which scientific validity and efficacy remain undefined. SUMMARY: Current tools for the diagnosis of OSA in children are labor-intensive, and onerous, and remain unvalidated. Novel diagnostic approaches linking objective physiological, biological, or both, measures to defined outcomes of pediatric OSA need to be developed and validated to enable wider and earlier recognition of this condition.
Authors: Hui-Leng Tan; David Gozal; Helena Molero Ramirez; Hari P R Bandla; Leila Kheirandish-Gozal Journal: Sleep Date: 2014-02-01 Impact factor: 5.849
Authors: Bernardo J Krause; Paola Casanello; Ana C Dias; Paulina Arias; Victoria Velarde; German A Arenas; Marcelo D Preite; Rodrigo Iturriaga Journal: Front Physiol Date: 2018-07-24 Impact factor: 4.566