Literature DB >> 19003744

Improvement of the quality of life concerning the health of patients with peripheral arterial disease (PAD) after successful bypass surgery.

W A Wohlgemuth1, O Safonova, M Engelhardt, M Freitag, K Wölfle, K Kirchhof.   

Abstract

BACKGROUND: To test whether quality of life depends on the psyche of patients after successful bypass surgery for peripheral arterial disease (PAD). PATIENTS AND METHODS: A total of 74 consecutive patients aged 36-69 years (57.7 +/- 8.8 years) with symptomatic PAD in the stages Fontaine IIb-IV were enrolled in a prospective study after successful bypass surgery. Because of bypass failure and one death during the study period, 11 of these patients were excluded from evaluation. Prior to surgery, Doppler sonography and digital subtraction angiography were carried out in all patients. Before and after revascularization, the ankle / brachial index (ABI) was determined in all study objects and the pain free walking distance (PFWD) in those with PAD stage Fontaine IIb. Health-related quality of life was measured by using the "Medical Outcomes Study Group Short Form 36" (SF-36), and personality was determined by employing the Psycho-Diagnostic-Test (PDT).
RESULTS: After surgery, there was an increase in ABI from 0.32 +/- 0.13 to 0.79 +/- 0.19 (p < .01), in PFWD from 42.6 m +/- 38.6 m to 419.7 m +/- 152.3 m (p < .01), and in the SF-36 scales "Physical functioning", "Bodily pain", "General health perceptions", and "Role-functioning physical" (p < .05). ABI correlated positively with "Bodily pain" (p < .01), "General health perceptions" (p < .01) and "Mental health" (p < .05). Among SF-36 and PDT-scales, "Role-functioning physical" correlated negatively with "Moodiness" / "Neuroticism" (p < .05), and "Social functioning" correlated positively with "General activity" (p < .01).
CONCLUSIONS: Whether objective clinical improvement increases quality of life mainly depends on the psyche of patients: A high level of general activity favors an improved quality of life and neurotic characteristics are more likely to be a hindrance.

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Year:  2008        PMID: 19003744     DOI: 10.1024/0301-1526.37.4.338

Source DB:  PubMed          Journal:  Vasa        ISSN: 0301-1526            Impact factor:   1.961


  3 in total

1.  In-depth analysis of cis-determinants that either promote or inhibit reinitiation on GCN4 mRNA after translation of its four short uORFs.

Authors:  Stanislava Gunišová; Petra Beznosková; Mahabub Pasha Mohammad; Vladislava Vlčková; Leoš Shivaya Valášek
Journal:  RNA       Date:  2016-01-28       Impact factor: 4.942

Review 2.  Please do not recycle! Translation reinitiation in microbes and higher eukaryotes.

Authors:  Stanislava Gunišová; Vladislava Hronová; Mahabub Pasha Mohammad; Alan G Hinnebusch; Leoš Shivaya Valášek
Journal:  FEMS Microbiol Rev       Date:  2018-03-01       Impact factor: 16.408

3.  Transition in Frailty State Among Elderly Patients After Vascular Surgery.

Authors:  Louise B D Banning; Linda Visser; Clark J Zeebregts; Barbara L van Leeuwen; Mostafa El Moumni; Robert A Pol
Journal:  World J Surg       Date:  2020-10       Impact factor: 3.352

  3 in total

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