| Literature DB >> 19003566 |
Natalya G Panova1, Cyril S Alexeev, Konstantin M Polyakov, Sergei A Gavryushov, Anatoliy M Kritzyn, Sergey N Mikhailov.
Abstract
Substrate specificity of E. coli thymidine phosphorylase to pyrimidine nucleoside modified at 5'-, 3'-, and 2'-positions of sugar moiety has been studied. Equilibrium (K(eq)) and kinetics constants of phosphorolysis reaction of nucleosides were measured. The most important hydrogen bonds in enzyme-substrate complex have been determined.Entities:
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Year: 2008 PMID： 19003566 DOI： 10.1080/15257770802257895
Source DB: PubMed Journal: Nucleosides Nucleotides Nucleic Acids ISSN： 1525-7770 Impact factor: 1.381