Literature DB >> 19000026

High divergence within the major HIV type 1 subtype B epidemic in Panama.

Sara Ahumada-Ruiz1, Concepción Casado, Iván Toala-González, Dario Flores-Figueroa, Amalia Rodríguez-French, Cecilio López-Galíndez.   

Abstract

The first molecular epidemiology study of human immunodeficiency virus type 1 (HIV-1) in Panama has been performed with plasma samples from 66 AIDS patients infected by different transmission routes and obtained from distinct locations. All samples were amplified by RT-PCR and sequenced in gag (p17) and env (C2-C4) genes. Phylogenetic analyses revealed that 64 (97%) of the samples belong to subtype B. We also identified the presence of two CRF, one CRF12_BF and one CRF02_AG. The most notable feature of the subtype B epidemic in Panama was the large genetic distance among isolates with a mean of 15.2% but reaching up to 31.3 % in env, indicating an epidemic with a long period of evolution.

Entities:  

Mesh：

Substances：

Year:  2008        PMID： 19000026     DOI： 10.1089/aid.2008.0153

Source DB:  PubMed          Journal:  AIDS Res Hum Retroviruses        ISSN： 0889-2229            Impact factor:   2.205


  7 in total

1.  A single early introduction of HIV-1 subtype B into Central America accounts for most current cases.

Authors:  Wendy Murillo; Nazle Veras; Mattia Prosperi; Ivette Lorenzana de Rivera; Gabriela Paz-Bailey; Sonia Morales-Miranda; Sandra I Juarez; Chunfu Yang; Joshua DeVos; José Pablo Marín; Mattias Mild; Jan Albert; Marco Salemi
Journal:  J Virol       Date:  2013-04-24       Impact factor: 5.103

Review 2.  Lentiviral delivery of short hairpin RNAs.

Authors:  N Manjunath; Haoquan Wu; Sandesh Subramanya; Premlata Shankar
Journal:  Adv Drug Deliv Rev       Date:  2009-03-31       Impact factor: 15.470

3.  Phylodynamics of HIV-1 from a phase III AIDS vaccine trial in Bangkok, Thailand.

Authors:  Marcos Pérez-Losada; David V Jobes; Faruk Sinangil; Keith A Crandall; Miguel Arenas; David Posada; Phillip W Berman
Journal:  PLoS One       Date:  2011-03-10       Impact factor: 3.240

4.  Evolutionary dynamics analysis of human metapneumovirus subtype A2: genetic evidence for its dominant epidemic.

Authors:  Jianguo Li; Lili Ren; Li Guo; Zichun Xiang; Gláucia Paranhos-Baccalà; Guy Vernet; Jianwei Wang
Journal:  PLoS One       Date:  2012-03-30       Impact factor: 3.240

5.  Molecular epidemiology of HIV-1 in Panama: origin of non-B subtypes in samples collected from 2007 to 2013.

Authors:  Yaxelis Mendoza; Gonzalo Bello; Juan Castillo Mewa; Alexander A Martínez; Claudia González; Claudia García-Morales; Santiago Avila-Ríos; Gustavo Reyes-Terán; Juan M Pascale
Journal:  PLoS One       Date:  2014-01-13       Impact factor: 3.240

6.  Human immunodeficiency virus type 1 (HIV-1) subtype B epidemic in Panama is mainly driven by dissemination of country-specific clades.

Authors:  Yaxelis Mendoza; Alexander A Martínez; Juan Castillo Mewa; Claudia González; Claudia García-Morales; Santiago Avila-Ríos; Gustavo Reyes-Terán; Blas Armién; Juan M Pascale; Gonzalo Bello
Journal:  PLoS One       Date:  2014-04-18       Impact factor: 3.240

7.  HIV-1 Antiretroviral Drug Resistance Mutations in Treatment Naïve and Experienced Panamanian Subjects: Impact on National Use of EFV-Based Schemes.

Authors:  Yaxelis Mendoza; Juan Castillo Mewa; Alexander A Martínez; Yamitzel Zaldívar; Néstor Sosa; Griselda Arteaga; Blas Armién; Christian T Bautista; Claudia García-Morales; Daniela Tapia-Trejo; Santiago Ávila-Ríos; Gustavo Reyes-Terán; Gonzalo Bello; Juan M Pascale
Journal:  PLoS One       Date:  2016-04-27       Impact factor: 3.240
  7 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.