Literature DB >> 18999089

Discovering synergistic qualities of published authors to enhance translational research.

Nathan J Bahr1, Aaron M Cohen.   

Abstract

Translational research is the process of bringing together basic scientific research and improvements in patient care. This process, by its very nature, requires a wide range of skills and resources, typically not found within any single individual. This project investigates the synergistic features of published researchers at the Oregon Clinical and Translational Research Institute(OCTRI) to see how scientists with different specializations can be brought together to improve translational research.The investigated features were author connectivity and complementarity of research subjects. Author connectivity was measured by taking the Average Path Length (APL) and cluster coefficients [1] over an OCTRIcoauthor network. A high degree of connectivity, or low APL value, would indicate that a researcher has participated in many collaborations and published many papers with other OCTRI researchers. This would imply that they have some experience we could leverage to build teams for translational research. Subject complementarity was established by using pairs of frequently co-occurring MeSH terms. Those terms were then used to bridge researchers together through indirect Swanson matching [2] and present evidence of topic synergy, or potential collaborative synergy.Our initial investigation supports the development of a collaborative browsing tool to assist the creation of new translational research teams. Such a tool is being developed at the OCTRI and will include a user-centric evaluation in the near future.

Entities:  

Mesh:

Year:  2008        PMID: 18999089      PMCID: PMC2655954     

Source DB:  PubMed          Journal:  AMIA Annu Symp Proc        ISSN: 1559-4076


  6 in total

1.  Obstacles facing translational research in academic medical centers.

Authors:  J S Pober; C S Neuhauser; J M Pober
Journal:  FASEB J       Date:  2001-11       Impact factor: 5.191

2.  Using ARROWSMITH: a computer-assisted approach to formulating and assessing scientific hypotheses.

Authors:  N R Smalheiser; D R Swanson
Journal:  Comput Methods Programs Biomed       Date:  1998-11       Impact factor: 5.428

Review 3.  Vitamin D and cancer.

Authors:  Minu M Ali; V Vaidya
Journal:  J Cancer Res Ther       Date:  2007 Oct-Dec       Impact factor: 1.805

4.  1alpha,25-Dihydroxyvitamin D3 down-regulates expression of prostate specific membrane antigen in prostate cancer cells.

Authors:  Rita E Serda; Marco Bisoffi; Todd A Thompson; Ming Ji; John L Omdahl; Laurel O Sillerud
Journal:  Prostate       Date:  2008-05-15       Impact factor: 4.104

5.  Translational Medicine: A two-way road.

Authors:  Francesco M Marincola
Journal:  J Transl Med       Date:  2003-07-24       Impact factor: 5.531

6.  Materializing research promises: opportunities, priorities and conflicts in translational medicine.

Authors:  John PA Ioannidis
Journal:  J Transl Med       Date:  2004-01-31       Impact factor: 5.531

  6 in total
  1 in total

1.  Evaluation of a prototype search and visualization system for exploring scientific communities.

Authors:  Michael E Bales; David R Kaufman; Stephen B Johnson
Journal:  AMIA Annu Symp Proc       Date:  2009-11-14
  1 in total

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